AZD1222

Products AZD1222 has been in the registration phase in the EU and many countries since the beginning of October 2020 as part of a rolling review and is not yet commercially available. The vaccine was developed at Oxford University’s Jenner Institute, spin-off Vaccitech and AstraZeneca. Efficacy and safety are being evaluated in studies involving up … AZD1222

Valaciclovir: Effects, Uses & Risks

Valaciclovir is one of the most commonly used agents to combat herpes simplex virus infection and shingles. The drug is incorporated into numerous preparations, is a prodrug, and is considered a virostatic agent. What is valaciclovir? Valaciclovir is a prodrug of aciclovir used in the therapy of herpes infections and shingles. The term prodrug is … Valaciclovir: Effects, Uses & Risks

Antiandrogens

Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens

Cellular Memory: Function, Tasks, Role & Diseases

The cellular memory hypothesis assumes information storage at the molecular genetic and cellular levels. The best-known example of cellular memory is with the antigen memory of the immune system. Meanwhile, the BMI1 protein of cellular memory is associated with carcinogenesis. What is cellular memory? The cellular memory hypothesis assumes information storage at the molecular genetic … Cellular Memory: Function, Tasks, Role & Diseases

Karyoplasm: Structure, Function & Diseases

The karyoplasm is the name given to the protoplasm within cell nuclei, which differs from the cytoplasm particularly in its electrolyte concentration. For DNA replication and transcription, the karyoplasm provides an optimal environment. In diabetic patients, nuclear inclusions of glycogen may be present in the karyoplasm. What is karyoplasm? Cell nuclei are located in the … Karyoplasm: Structure, Function & Diseases

Intercalation: Function, Tasks, Role & Diseases

Intercalation is the intercalation of particles such as molecules or ions into certain chemical compounds such as crystal lattices. In biochemistry, the term is associated with the intercalation of particles between adjacent base pairs of DNA, which can result in lattice mutations. Intercalary properties are possessed, for example, by the substance thalidomide, which has spawned … Intercalation: Function, Tasks, Role & Diseases

Elvitegravir

Products Elvitegravir is commercially available as film-coated tablets in fixed combination with other antiretroviral agents and cobicistat (Stribild, successor: Genvoya). It has been approved in many countries since 2013. Stribild: elvitegravir, cobicistat, emtricitabine, and tenofovirdisoproxil. Genvoya: elvitegravir, cobicistat, emtricitabine and tenofoviralafenamide. Structure and properties Elvitegravir (C23H23ClFNO5, Mr = 447.9 g/mol) is a dihydroquinolone derivative. It … Elvitegravir

Height and Body Weight

The influence of genes on the human body has been the subject of intense scientific research for many years. Although great progress has already been made in decoding the human genome, there are still some controversial points: What part do genes as well as environmental influences play in the expression of certain physical and psychological … Height and Body Weight

Aneuploidy Screening: Treatment, Effects & Risks

Aneuploidy screening is used to detect numerical chromosomal aberrations in embryos created in vitro and intended for implantation. It is a cytogenetic test that can only detect numerical aberrations of specific chromosomes. Aneuploidy screening thus represents a form of preimplantation genetic diagnosis (PGD). What is aneuploidy screening? Aneuploidy screening is used only in in vitro … Aneuploidy Screening: Treatment, Effects & Risks