Products Quinagolide is commercially available in tablet form (Norprolac). It has been approved in many countries since 1994. Structure and properties Quinagolide (C20H33N3O3S, Mr = 395.56 g/mol) is a non-ergoline dopamine agonist with a similar structure to apomorphine. It is present in drugs as quinagolide hydrochloride. Effects Quinagolide (ATC G02CB04) has dopaminergic properties and inhibits … Quinagolide
Products Monk’s pepper extracts are commercially available as film-coated tablets and drops, among others. Stem plant Monk’s pepper L. belongs to the verbenaceae family. The shrub, which grows up to several meters high, is native to the Mediterranean region, Central Asia and India. Monk’s pepper has been used since ancient times to treat women’s ailments. … Monk Pepper
Products Cabergoline is commercially available in tablet form (Cabaser, Dostinex). It has been approved in many countries since 1995. Structure and properties Cabergoline (C26H37N5O2, Mr = 451.6 g/mol) is a dopaminergic ergoline derivative. It exists as a white crystalline powder that is practically insoluble in water. Effects Cabergoline (ATC N04BC06) has dopaminergic properties and reduces … Cabergoline
Symptoms Restless legs syndrome manifests as an uncomfortable and difficult-to-describe feeling in the legs and a strong urge to move the legs. Less commonly, the arms are also affected. The unilateral or bilateral insensations include, for example, a burning sensation, pain, pressing, creeping and a pulling sensation. The discomfort occurs mainly at rest, for example, … Restless Legs Syndrome Causes and Treatment
Symptoms Infection with norovirus manifests as gastroenteritis with diarrhea without blood in the stool and/or with violent, even explosive vomiting. Vomiting is more common in children. Furthermore, accompanying symptoms such as nausea, bloating, abdominal pain, abdominal cramps, muscle pain, headache, and mild fever may occur. An asymptomatic course is also possible. The duration of the … Norovirus
Effects Diphenylbutylpiperidines are antidopaminergic, antipsychotic, and antiemetic. Mechanism of action Dopamine antagonists Indications Clinical pictures of the schizophrenic type. Structure and properties Derivatives of diphenylbutylpiperidine. Active ingredients Penfluridol (Semap, off label). Fluspirilen (IMPA, D) Pimozide (out of commerce)
Products Antiemetics are commercially available in the form of tablets, as melting tablets, as solutions (drops), and injectables, among others. They are also administered as suppositories because peroral administration is not possible. In many countries, the best-known antiemetics include domperidone (Motilium, generic) and meclozine, which, along with caffeine and pyridoxine, is contained in Itinerol B6. … Antiemetics: Drugs against Nausea or Vomiting
Symptoms The preliminary stages are fatigue, yawning, difficulty concentrating, headache, mood swings, lethargy, and an increased need for sleep. The actual motion sickness manifests itself acutely in symptoms such as cold sweat, pallor, pale complexion, sensations of warmth and cold, faintness, hyperventilation, rapid pulse rate, low blood pressure, salivation, nausea, nausea, vomiting, and dizziness. Triggers … Motion Sickness
Products Bromocriptine is commercially available in tablet form (Parlodel). It was developed at Sandoz in the 1960s and has been approved in many countries since 1975. Generic versions are now available in many countries. Structure and properties Bromocriptine (C32H40BrN5O5, Mr = 654.6 g/mol) is a brominated derivative of the natural ergot alkaloid ergocryptine. It is … Bromocriptine
Products Uprima sublingual tablets (2 mg, 3 mg) for erectile dysfunction are no longer marketed in many countries. The marketing authorization was not renewed by Abbott AG in 2006. Commercial reasons were cited, probably attributed to competition from phosphodiesterase-5 inhibitors (e.g., sildenafil, Viagra). It is also possible that a post-marketing study had played a role, … Apomorphine
Products Rotigotine is commercially available as a transdermal patch in various potencies (Neupro). It was approved in many countries in 2006 as the first TTS for Parkinson’s disease therapy. Structure and properties Rotigotine (C19H25NOS, Mr = 315.5 g/mol) is an aminotetralin and thiophene derivative structurally related to dopamine. It has a non-ergoline structure and exists … Rotigotine
Products Ropinirole is commercially available in the form of film-coated tablets (Adartrel, Requip, generic). It has been approved in many countries since 1996. Structure and properties Ropinirole (C16H24N2O, Mr = 260.4 g/mol) is a non-ergoline dopamine agonist and a dihydroindolone derivative. It is present in drugs as ropinirole hydrochloride, a white to yellow powder that … Ropinirole
