Imiglucerase

Products Imiglucerase is commercially available as a powder for the preparation of an infusion solution (Cerezyme). It has been approved in many countries since 1999. Structure and properties Imiglucerase is an enzyme produced by biotechnological methods. The glycoprotein consists of 497 amino acids. The sequence differs in one amino acid from the natural acid beta-glucocerebrosidase. … Imiglucerase

Naratriptan: Drug Effects, Side Effects, Dosage and Uses

Products Naratriptan is commercially available in the form of film-coated tablets (Naramig). It has been approved in many countries since 1997. Structure and properties Naratriptan (C17H25N3O2S, Mr = 335.5 g/mol) is structurally related to serotonin and is an indole and piperidine derivative. It is present in drugs as naratriptan hydrochloride, a white to slightly yellowish … Naratriptan: Drug Effects, Side Effects, Dosage and Uses

PCSK9 Inhibitors

Products Alirocumab was approved in the United States in 2015 as the first agent in the group of PCSK9 inhibitors in the form of a solution for injection (Praluent). Evolocumab (Repatha) followed as the second agent in the EU, also in 2015. Structure and properties PCSK9 inhibitors to date are monoclonal antibodies that must be … PCSK9 Inhibitors