Products and withdrawal from the market Sibutramine was approved in 1999 and was commercially available in many countries in 10- and 15-mg capsule form (Reductil, Abbott AG). On March 29, 2010, Abbott AG, in consultation with Swissmedic, informed the public that the marketing authorization had been suspended. Since then, sibutramine may no longer be prescribed … Sibutramine
Effects Antiadiposita differ in their effects. They inhibit appetite or increase satiety, reduce the absorption of food components in the intestine or promote their utilization, increase energy metabolism and degrading metabolic processes. The ideal slimming agent would enable rapid, high and stable weight loss and at the same time be very well tolerated and applicable … Slimming Products
Products Most antidepressants are commercially available in the form of film-coated tablets. In addition, oral solutions (drops), meltable tablets, dispersible tablets, and injectables are also available, among others. The first representatives were developed in the 1950s. It was discovered that the antituberculosis drugs isoniazid and iproniazid (Marsilid, Roche) had antidepressant properties. Both agents are MAO … Antidepressants
Products Duloxetine is commercially available in the form of capsules (Cymbalta, generic). It has been approved in many countries since 2005. Structure and properties Duloxetine (C18H19NOS, Mr = 297.4 g/mol) is present in drugs as pure -duloxetine hydrochloride, a white to light brown powder that is sparingly soluble in water. Effects Duloxetine (ATC N06AX21) has … Duloxetine
Symptoms Fibromyalgia is a chronic, noninflammatory disorder that manifests as pain throughout the body and is characterized by numerous other complaints. It is much more common in women than in men and usually first appears in middle age. Chronic, bilateral, diffuse pain. Muscle pain, pain in the limbs, back pain, joint pain, neck pain, headaches, … Fibromyalgia Causes and Treatment
Duloxetine is an antidepressant and works by increasing levels of norepinephrine and serotonin to increase drive and improve mood. Duloxetine is therefore used primarily in the treatment of depression. Another major area of application is stress incontinence in women, as the active ingredient strengthens the bladder and pelvic floor muscles. Learn more about the effects, … How Duloxetine Works for Depression and Incontinence
Products Ciprofloxacin is commercially available as film-coated tablets, oral suspension, infusion preparation, eye drops, eye ointment (Ciloxan), and ear drops (Ciproxin HC + hydrocortisone). In addition to the original Ciproxin, various generics are available. Ciprofloxacin was approved in many countries in 1987. This article refers to peroral administration. Structure and Properties Ciprofloxacin (C17H18FN3O3, Mr = … Ciprofloxacin
Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment
Symptoms Urinary incontinence manifests as involuntary leakage of urine. The common problem poses a psychosocial challenge for those affected, which can lead to changes in personal activities and a loss of quality of life. Risk factors include female gender, age, obesity, and numerous medical conditions. Causes Urinary incontinence can occur as a result of pathologic, … Urinary Incontinence: Causes and Treatment
Introduction The so-called serotonin noradrenaline reuptake inhibitors (SNRI) are mainly drugs used in the treatment of depression. The most important active ingredients in this class of drugs are venlafaxine and duloxetine. The name refers to the ability of these drugs to exert their effect on both serotonin and noradrenalin levels in the central nervous system. … SNRI
Effect of SNRI As described above and as can be seen from the name, serotonin noradrenalin reuptake inhibitors (SNRI) inhibit the reuptake of serotonin and noradrenalin into the nerve cells. In order to understand this mechanism, one should consider the structure of a synapse, i.e. an interconnection point between two nerve cells. A synapse consists … Effect of SNRI | SNRI
When should SNRI not be given? SNRIs must not be used if an intolerance and allergic reaction to the active substance has occurred. The use of so-called MAOIs, the irreversible monoamine oxidase inhibitors, is also considered a strict contraindication.These are drugs used to treat depression or Parkinson’s disease. If taken at the same time or … When should SNRI not be given? | SNRI
