Enterohepatic Circulation

Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation

Elimination

Introduction Elimination is a pharmacokinetic process that describes the irreversible removal of active pharmaceutical ingredients from the body. It is composed of biotransformation (metabolism) and excretion (elimination). The most important organs for excretion are the kidney and the liver. However, drugs can also be excreted through the respiratory tract, hair, saliva, milk, tears, and sweat. … Elimination

Trent

Products Trientine was approved in many countries in 2020 in capsule form (Triogen). Structure and properties Trientine is present in the drug as trientine dihydrochloride, a white to slightly yellow hygroscopic powder that is readily soluble in water. It is triethylenetetramine. Effects Trientine (ATC A16AX12) forms a stable and soluble complex with copper. It promotes … Trent

Protraction: Effect, Uses & Risks

In anatomy, protraction corresponds to a forward movement of individual body structures. The opposite movement is retraction. The increased protraction of the chin, for example, can promote a herniated disc in the long term. What is protraction? In anatomy, protraction plays a role as a movement term, especially in connection with the scapula, for example. … Protraction: Effect, Uses & Risks

Famotidine

Products Famotidine is not commercially available in many countries. In Germany and other countries, it is available in the form of film-coated tablets. Structure and properties Famotidine (C8H15N7O2S3, Mr = 337.4 g/mol) exists as a white to yellowish-white crystalline powder or as crystals and is very sparingly soluble in water. It is a thiazole derivative … Famotidine

Volume of Distribution

Definition and examples When a drug is administered, for example, a tablet is swallowed or an injection is injected into a vein, the active pharmaceutical ingredients subsequently spread throughout the body. This process is called distribution. Active ingredients distribute throughout the bloodstream, into tissues, and are eliminated through metabolism and excretion. Mathematically, the volume of … Volume of Distribution

Excretion: Function, Tasks, Role & Diseases

By excretion, physicians mean the release of certain metabolic products into the environment. Without excretion, the balance in metabolism would be disturbed and poisoning by metabolic products such as ammonia could occur. Disturbed excretion is present, for example, in the group of storage diseases. What is excretion? Excretion is the excretion of unwanted or unusable … Excretion: Function, Tasks, Role & Diseases

Physical examination

A physical examination is part of every medical examination. The physical examination performed differs from the doctor who performs it. This difference is due on the one hand to the symptoms of the patient and on the other hand to the specialty of the examining physician. A complete physical examination takes a relatively long time, … Physical examination

Secretion: Function, Tasks, Role & Diseases

Glands or gland-like cells release a substance into the body during secretion. The secretion is released either internally via blood pathways or externally via glandular pathways. Overproduction of certain secretions is called hypersecretion, whereas underproduction is called hyposecretion. What is secretion? Many secretions are also used for digestion, such as the secretion of digestive enzymes … Secretion: Function, Tasks, Role & Diseases