Products Cimetidine was commercially available in the form of film-coated tablets (Tagamet). Currently, there are no longer any human medicines registered with the active ingredient in many countries. Cimetidine was developed in the 1960s and 1970s under the leadership of Sir James Black as the first wirsktoff from the group of H2 receptor antagonists and … Cimetidine
Products No finished drug products containing roxatidine are commercially available in many countries. Structure and properties Roxatidine (C17H26N2O3, Mr = 306.4 g/mol) is present in the drug as roxatidine acetate, a prodrug that is metabolized in the body to the active drug. Effects Roxatidine (ATC A02BA06) inhibits the secretion of gastric acid and pepsin in … Roxatidine
Products Nizatidine is not commercially available in many countries and Germany. In the United States, capsules and film-coated tablets, among other products, have been on the market since 1992. Structure and properties Nizatidine (C12H21N5O2S2, Mr = 331.5 g/mol) is a thiazole derivative and an organic cation. It exists as a white crystalline substance that is … Nizatidine
Products Famotidine is not commercially available in many countries. In Germany and other countries, it is available in the form of film-coated tablets. Structure and properties Famotidine (C8H15N7O2S3, Mr = 337.4 g/mol) exists as a white to yellowish-white crystalline powder or as crystals and is very sparingly soluble in water. It is a thiazole derivative … Famotidine
Products Ranitidine was commercially available in the form of film-coated tablets, effervescent tablets, and as a solution for injection and had been approved since 1981 (Zantic, generic). Currently, drugs containing ranitidine are no longer available in many countries. Starting in 1996, tablets for self-medication with 75 mg were released. However, they are now also no … Ranitidine: Drug Effects, Side Effects, Dosage and Uses
Products No finished drug products containing lafutidine are commercially available in many countries. Structure and properties Lafutidine (C22H29N3O4S, Mr = 431.5 g/mol) Effects Lafutidine (ATC A02BA08) inhibits gastric acid and pepsin secretion in the stomach. Effects are due to antagonism at histamine H2 receptors. Indications For the treatment of gastric acid-associated disorders (eg, gastric distention, … Lafutidin
