expectorants

Cystic Fibrosis: Causes and Treatment

Symptoms In cystic fibrosis (CF, cystic fibrosis), different organ systems are affected, resulting in a heterogeneous clinical picture with symptoms of varying severity: Lower respiratory tract: Chronic cough with viscous mucus formation, obstruction, recurrent infectious diseases, e.g., with , inflammation, remodeling of the lungs (fibrosis), pneumothorax, respiratory insufficiency, shortness of breath, wheezing, oxygen deficiency. Upper … Cystic Fibrosis: Causes and Treatment

Dihydrocodeine

Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine

Ammonium Chloride

Products In many countries, human medicines with ammonium chloride as the active ingredient are no longer on the market. The salt is an ingredient in Mixtura solvens (Dissolving Mixture PH) and licorice. It used to be included in Bisolvon Linctus syrup along with bromhexine. In some countries, expectorants are available. Structure and properties Ammonium chloride … Ammonium Chloride

Rhinathiol Promethazine

Withdrawal from the market Rhinathiol Promethazine (Sanofi-Aventis Suisse SA, category C) contained a combination of the sedative antihistamine promethazine and the expectorant mucolytic carbocisteine. According to the package insert, the syrup could be taken for both productive cough and irritable cough (1). It was frequently used in children. The drug was withdrawn from the market … Rhinathiol Promethazine

Earache Causes and Treatment

Symptoms Pain in the ear (technical term: otalgia) can be unilateral or bilateral and persistent or intermittent. They vary in intensity and nature, can be extremely uncomfortable, and sometimes go away on their own. Ear pain is often accompanied by other symptoms, such as a discharge from the ear canal, difficulty hearing, a feeling of … Earache Causes and Treatment

Codeine: Drug Effects, Side Effects, Dosage and Uses

Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses

Carbocistein

Products Carbocisteine is commercially available as a syrup (e.g., rhinathiol, co-marketing drugs, generics). In combination with xylometazoline, it is also found in decongestants and nasal drops (Triofan). Structure and properties Carbocisteine or -carboxymethylcysteine (C5H9NO4S, Mr = 179.2 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a carboxymethyl derivative … Carbocistein

Ambroxol (Mucosolvan)

Products Ambroxol is commercially available in the form of lozenges, sustained-release capsules, and syrup (e.g., Mucosolvon), among others. It has been approved in many countries since 1982. Structure and properties Ambroxol (C13H18Br2N2O, Mr = 378.1 g/mol) is present in drugs as ambroxol hydrochloride, a white to yellowish crystalline powder that is sparingly soluble in water. … Ambroxol (Mucosolvan)

Butamirate

Products Butamirate is commercially available as a syrup, drops, and depot tablets (e.g., NeoCitran cough suppressant, formerly Sinecod). It has been approved in many countries since 1965. Structure and properties Butamirate (C18H29NO3, Mr = 307.4 g/mol) is present in drugs as butamirate dihydrogen citrate. It has structural similarities to the antitussive butetamate. Butamirate is not … Butamirate

GeloMyrtol

Products GeloMyrtol is commercially available in the form of enteric-coated soft capsules. It was newly registered in many countries in October 2011, and has been on the market in Germany for years. GeloMyrtol is equivalent to GeloDurant, which was formerly marketed as Sibrovita. Composition The capsules contain Myrtol, a distillate of a blend of eucalyptus … GeloMyrtol

Antitussives

Products Antitussives are commercially available in the form of tablets, capsules, as cough syrups, and drops, among others. Structure and properties Antitussives do not have a uniform chemical structure. However, many are derived from natural opium alkaloids (opioids). Effects Antitussives have cough-irritating (antitussive) properties. They reduce the frequency and intensity of coughing attacks. Their effects … Antitussives

Hydrocodone

Products Hydrocodone was commercially available in tablet form in many countries between 1971 and 2018 (Hydrocodone Streuli, off label). In the United States, it is available in combination with acetaminophen (Vicodin, generic). Structure and properties Hydrocodone (C18H21NO3, Mr = 299.4 g/mol) is present in drugs as hydrocodontartrate (- 2.5 H2O), a white crystalline powder that … Hydrocodone