Erdostein

Products Erdostein is commercially available in the form of capsules (Mucofor). It was developed at Edmond Pharma in Milan, Italy, and has been approved in many countries since 1994. Structure and properties Erdostein (C8H11NO4S2, Mr = 249.3 g/mol) is a prodrug. The effects are mediated by the free sulfhydryl groups (-SH) of the metabolites. The … Erdostein

Ammonium Chloride

Products In many countries, human medicines with ammonium chloride as the active ingredient are no longer on the market. The salt is an ingredient in Mixtura solvens (Dissolving Mixture PH) and licorice. It used to be included in Bisolvon Linctus syrup along with bromhexine. In some countries, expectorants are available. Structure and properties Ammonium chloride … Ammonium Chloride

Carbocistein

Products Carbocisteine is commercially available as a syrup (e.g., rhinathiol, co-marketing drugs, generics). In combination with xylometazoline, it is also found in decongestants and nasal drops (Triofan). Structure and properties Carbocisteine or -carboxymethylcysteine (C5H9NO4S, Mr = 179.2 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a carboxymethyl derivative … Carbocistein

Ambroxol (Mucosolvan)

Products Ambroxol is commercially available in the form of lozenges, sustained-release capsules, and syrup (e.g., Mucosolvon), among others. It has been approved in many countries since 1982. Structure and properties Ambroxol (C13H18Br2N2O, Mr = 378.1 g/mol) is present in drugs as ambroxol hydrochloride, a white to yellowish crystalline powder that is sparingly soluble in water. … Ambroxol (Mucosolvan)

GeloMyrtol

Products GeloMyrtol is commercially available in the form of enteric-coated soft capsules. It was newly registered in many countries in October 2011, and has been on the market in Germany for years. GeloMyrtol is equivalent to GeloDurant, which was formerly marketed as Sibrovita. Composition The capsules contain Myrtol, a distillate of a blend of eucalyptus … GeloMyrtol

Dissolving Mixture

Products Solubilizing Mixture is not commercially available as a finished drug product and must be freshly prepared at a pharmacy or drugstore if needed. Structure and properties The mixture is a clear, dark brown liquid with a faint odor of alcoholic liquorice extract. Production Ammonium chloride 2.5 g Adjusted ethanolic licorice root fluid extract. 7.5 … Dissolving Mixture

Bromhexine

Products Bromhexine is commercially available as tablets, syrup, and solution (Bisolvon). It has been approved in many countries since 1966. Structure and properties Bromhexine (C14H20Br2N2, Mr = 376.1 g/mol) is a brominated aniline and benzylamine derivative. It is present in drugs as bromhexine hydrochloride, a white crystalline powder that is very sparingly soluble in water. … Bromhexine

Fir Tip Syrup

Products Fir tip syrup is available in many countries, for example, from A. Vogel (Santasapina, A. Vogel fir tip syrup, also as cough drops) and as a home specialty on the market, for example, the Bündner Bergwaldsirup. It can also be made by yourself. Ingredients Fir tip syrup usually contains an extract from the branch … Fir Tip Syrup

Guaifenesin

Products Guaifenesin is commercially available as a syrup and in the form of drops (e.g., NeoCitran cough suppressant, formerly Resyl, combination products, Resyl plus). It has been approved in many countries since 1946. Structure and properties Guaifenesin (C10H14O4, Mr = 198.2 g/mol) is the glycerol ether of guaiacol, a natural substance found in guaiacol trees. … Guaifenesin

N-Acetylcysteine

Products N-acetylcysteine is found in numerous products, including ACC Sandoz (formerly ACC eco), Ecomucyl, Fluimucil, Mucostop, and Solmucol. The original Fluimucil was first approved in many countries in 1966. Acetylcysteine is usually administered perorally in the form of effervescent tablets, lozenges, lingual tablets, powders, granules, capsules or syrups. Injection solutions, ampoules for aerosol devices, and … N-Acetylcysteine