Finasteride: Effects, Applications, Side Effects

How finasteride works Finasteride is a drug from the class of 5-alpha-reductase inhibitors. 5-alpha-reductase is an enzyme responsible for converting testosterone into the active form 5-alpha-dihydrotestosterone (DHT). The hormone testosterone is primarily responsible for the formation of male sexual characteristics and is found everywhere in the human body. When testosterone is converted by 5-alpha-reductase, DHT … Finasteride: Effects, Applications, Side Effects

Erectile Dysfunction: Causes and Treatment

Symptoms Erectile dysfunction or so-called erectile dysfunction refers to the persistent or recurrent inability to achieve or maintain an erection, which is necessary for sexual activity. This makes sexual intercourse impossible and severely limits sexual life. For the affected man, erectile dysfunction can be a great psychological burden. It can trigger stress, negatively affect self-esteem … Erectile Dysfunction: Causes and Treatment

Dispensing Categories of Medicinal Products

Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products

5Α-Reductase Inhibitors

Products 5α-Reductase inhibitors are commercially available in many countries in the form of film-coated tablets and capsules. Finasteride was the first agent from this group to be approved in 1993 (USA: 1992). There are two finasteride drugs on the market. One with 5 mg for the treatment of prostate enlargement (Proscar, generic) and one with … 5Α-Reductase Inhibitors

Finasteride

Products Finasteride is commercially available as film-coated tablets (prostate: Proscar, generic, 5 mg; hair loss: Propecia, generic, 1 mg). It has been approved in many countries since 1993. Propecia was launched five years later, in 1998. Structure and properties Finasteride (C23H36N2O2, Mr = 372.5 g/mol) is a 4-azasteroid and structurally related to testosterone. It exists … Finasteride

Post-finasteride Syndrome: Causes, Symptoms & Treatment

Post-finasteride syndrome (PFS) represents a complex of symptoms due to the side effects of the drug finasteride. These are persistent neurological, sexual, and physical side effects. Even after discontinuation of the drug, the symptoms sometimes persist for a long time. What is post-finasteride syndrome? Post-finasteride syndrome is a term defined by doctors, the media, and … Post-finasteride Syndrome: Causes, Symptoms & Treatment

Androgenetic Alopecia in Men

Symptoms Hereditary hair loss in men begins at the temples (“receding hairline”) and continues to the crown and back of the head, with progressive thinning and the typical M-shaped pattern. Over time, all that may remain of the once lush head of hair is a bald spot and a crown of hair. Unlike telogen effluvium, … Androgenetic Alopecia in Men

Prostate Enlargement Causes and Treatment

Symptoms Benign hyperplasia of the prostate is a typical and chronic age-related condition in men. Approximately 50% of men over 50 and 80% of men over 80 are affected. The incidence and symptoms increase with age. Age is therefore the most important risk factor. The clinical symptoms are also called “benign prostatic syndrome”, because the … Prostate Enlargement Causes and Treatment

Hormonal Hereditary Hair Loss (Alopecia Androgenetica): Causes, Symptoms & Treatment

Alopecia androgenetica is hormonal hereditary hair loss caused by an inborn hypersensitivity of hair follicles to the male sex hormone testosterone. Approximately 80 percent of men and nearly 50 percent of women suffer from hormone-hereditary hair loss during their lifetime. What is hormonal hereditary hair loss? Hormonal hereditary hair loss (alopecia androgenetica) is hair loss … Hormonal Hereditary Hair Loss (Alopecia Androgenetica): Causes, Symptoms & Treatment

Hair Loss: Causes, Treatment & Help

Hair loss or baldness does not only occur in men. Often women are also affected by hair loss. As the term itself already reveals, hair loss is an increased loss of head hair, occasionally also the pubic hair or other body hair. Basically, there are different forms of hair loss, which can have different causes. … Hair Loss: Causes, Treatment & Help

Finasteride: Effects, Uses & Risks

Finasteride belongs to the synthetic steroids and is used to treat hereditary hair loss in men, as well as prostatic hyperplasia. What is finasteride? Finasteride belongs to the synthetic steroids and is used, for example, to treat hereditary hair loss in men. Finasteride is a drug that was originally developed to treat benign enlargement of … Finasteride: Effects, Uses & Risks

Dutasteride

Products Dutasteride is commercially available in capsule form (Avodart). It is also available in combination with the alpha blocker tamsulosin (Duodart); see dutasteride tamsulosin. The active ingredient has been approved in many countries since 2003. Generics were registered in 2017. Generic versions of Duodart were approved in 2018. Structure and properties Dutasteride (C27H30F6N2O2, Mr = … Dutasteride