Products Eliglustat is commercially available in the form of hard capsules (Cerdelga). It was approved in many countries in 2020. Structure and properties Eliglustat (C23H36N2O4, Mr = 404.5 g/mol) is present in the drug as eliglustat tartrate. Eliglustat is an analog of glucocerebroside. Effects Eliglustat (ATC A16AX10) is a specific inhibitor of the enzyme glucosylceramide … Eliglustat
Products Velaglucerase alfa is commercially available as a powder for the preparation of an infusion solution (Vpriv). It has been approved in many countries since 2011. Structure and properties Velaglucerase alfa is an enzyme and glycoprotein with 497 amino acids and the same sequence as natural glucocerebrosidase. Glycosylation with mannose results in velaglucerase alfa being … Velaglucerase Alfa
Products Taliglucerase alfa is commercially available as an infusion preparation in some countries (Elelyso). It has not yet been registered in many countries. Structure and properties Taliglucerase alfa is an enzyme and an analog of natural glucocerebrosidase, from which it differs in several amino acids. Glycosylation with mannose results in the uptake of taliglucerase alfa … Taliglucerase Alfa
Products Miglustat is commercially available in capsule form (Zavesca, generic). It has been approved in many countries since 2004. Structure and properties Miglustat (C10H21NO4, Mr = 219.3 g/mol) is an -alkylated iminosugar. It exists as a white crystalline powder with a bitter taste that is readily soluble in water. Effects Miglustat (ATC A16AX06) is an … Miglustat
