Induced-fit: Function, Tasks, Role & Diseases
The induced-fit theory originated with Koshland and corresponds to an extension of the lock-and-key principle, which assumes that anatomical structures fit together. Induced-fit refers to enzymes such as kinase that change their conformation to form an enzyme-ligand complex. In enzyme defects, the induced-fit principle may be affected by perturbations. What is induced-fit? There is binding … Induced-fit: Function, Tasks, Role & Diseases