What is Glutamate?

Glutamate is a natural product of plant protein. Meat, fish, vegetables and milk – in other words, foods containing protein – contain the nutrient, which is essential for many important life functions: it helps build and break down body cells, strengthens nerves and supports brain function. Glutamate is even a component of breast milk. But … What is Glutamate?

Neurotransmitters: Structure, Function & Diseases

Neurotransmitters are something like the couriers of our body. They are biochemical substances that have the task of transmitting signals from one nerve cell (neuron) to the next. Without neurotransmitters, the control of our body would be completely impossible. What are neurotransmitters? The term neurotransmitter already describes the usefulness of these messenger substances very well, … Neurotransmitters: Structure, Function & Diseases

Memantine

Products Memantine is commercially available as film-coated tablets, meltable tablets, and oral solution (Axura, Ebixa). It has been approved in many countries since 2003. Generic versions were registered in 2014. Structure and properties Memantine (C12H21N, Mr = 179.3 g/mol) is present in drugs as memantine hydrochloride, a white powder that is insoluble in water. Memantine … Memantine

Shiitake

Products The fresh or dried shiitake is available in grocery stores and specialty stores. It is one of the most widely consumed edible mushrooms in the world after the cultivated mushroom. Mushroom The shiitake mushroom is native to East Asia and has been cultivated for centuries – including in many countries today. In nature, it … Shiitake

Valine: Function & Diseases

Valine represents a branched-chain essential amino acid. In addition to body composition, it is also used for energy production in situations of special performance requirements. The need for valine is particularly high in competitive athletes. What is valine? Valine is a branched-chain amino acid that is essential for the body. Due to the branched hydrocarbon … Valine: Function & Diseases

Vestibulospinal Reflex: Function, Role & Diseases

The vestibulospinal reflex is a brainstem reflex whose circuitry involves the vestibular organ and nuclei vestibulares. Activation of the reflex causes contraction of the extensor muscles while inhibiting the flexor muscles of the extremities. In decerebration rigidity, the reflex becomes prominent. What is the vestibulospinal reflex? A brainstem reflex is known as the vestibulospinal reflex, … Vestibulospinal Reflex: Function, Role & Diseases

Pregabalin

Products Pregabalin is commercially available in capsule form and as an oral solution (Lyrica, generics). It was approved in the United States and EU in 2004 and in many countries in 2005. Structure and properties Pregabalin (C8H17NO2, Mr = 159.2 g/mol) exists as a white crystalline powder that is soluble in water. It was developed … Pregabalin

Auxiliary Materials

Definition On the one hand, drugs contain the active ingredients that mediate the pharmacological effects. On the other hand, they consist of excipients, which are used for the production or to support and regulate the drug effect. Placebos, which consist only of excipients and contain no active ingredients, are an exception. Excipients can be of … Auxiliary Materials

Fluralaner

Products Fluralaner is commercially available as a veterinary drug in the form of chewable tablets and as a spot-on preparation (Bravecto). It was approved in many countries in 2015. Structure and properties Fluralaner (C22H17Cl2F6N3O3, Mr = 556.3 g/mol) is present in drugs as a racemate. It is a fluorinated isoxazoline-substituted benzamide. Effects Fluralaner (ATCvet QP53BX05) … Fluralaner

Perampanel

Products Perampanel is commercially available in the form of film-coated tablets (Fycompa). It has been approved in many countries since late 2012. In 2020, an oral suspension was also registered. Structure and properties Perampanel (C23H15N3O, Mr = 349.4 g/mol) is a pyridine derivative. It exists in the drug as a white to yellowish powder that … Perampanel