Products Follitropin alfa is commercially available as an injectable. It has been approved in many countries since 1995. Biosimilars are approved in some countries (Switzerland: Ovaleap, 2018). Structure and properties Follitropin alfa is a follicle-stimulating hormone (FSH) produced by biotechnological methods. It is a heterodimer and consists of two distinct glycoproteins, the α-subunit (92 amino … Follitropin Alfa
Products Follitropin beta is commercially available as a solution for injection (Puregon). It has been approved in many countries since 2001. Structure and properties Follitropin beta is a recombinant human follicle-stimulating hormone (FSH) produced by biotechnological methods. The amino acid sequence corresponds to human FSH. It differs from follitropin alfa in glycosylation. FSH is a … Follitropin Beta
Products Follitropin delta was approved in the EU in 2016 and in many countries in 2017 as [solution for injection>injections] (recovelle). Structure and properties Follitropin delta is a recombinant human follicle-stimulating hormone (FSH) with the same amino acid sequences as the natural hormone. Follitropin delta is produced in the human cell line PER.C6 and differs … Follitropin Delta
Products Clomiphene was commercially available in tablet form (Serophene, Clomid). It was approved in many countries since 1967 and is currently no longer available. Drugs containing the active ingredient can be imported from abroad. Structure and properties Clomiphene (C26H28ClNO, Mr = 405.95 g/mol) is a nonsteroidal triphenylethylene derivative that exists as an unequal mixture of … Citalopram: Drug Effects, Side Effects, Dosage and Uses
Products Danazol was commercially available in many countries in the form of capsules and had been approved since 1977 (Danatrol). No finished drug products have since been registered. Structure and properties Danazol (C22H27NO2, Mr = 337.5 g/mol) is an isoxazole derivative of ethisterone related to testosterone. Danazol exists as a white to slightly yellow crystalline … Danazol
Products Therapeutic proteins are usually administered in the form of injection and infusion preparations and must be stored in a refrigerator. The first recombinant protein to be approved was human insulin in 1982. Some proteins, for example, are also available in tablet, capsule, and powder form and can be stored at room temperature, such as … Therapeutic Proteins
Products Urofollitropin is commercially available as an injectable (fostimone). It has been approved in many countries since 1996. Structure and properties Urofollitropin is a highly purified human follicle-stimulating hormone (FSH) derived from the urine of postmenopausal women. FSH is a heterodimer and consists of two distinct glycoproteins, the α-subunit (92 amino acids) and the β-subunit … Urofollitropin
Products Menotropin is commercially available as an injectable (Menopur, Merional HG, combination products). It has been used medicinally since the 1960s. Structure and properties Menotropin is a highly purified human menopausal gonadotropin (hMG, ) derived from human urine of postmenopausal women. Argentina and China are reported as the countries of origin. Menotropin is a mixture … Menotropin
Products Lutropin alfa is commercially available as an injectable (Luveris). It has been approved in many countries since 2002. Structure and properties Lutropin alfa is a is a recombinant human luteinizing hormone (LH). LH is a glycoprotein. Indications In combination with follicle-stimulating hormone (FSH) to stimulate follicular maturation in women with severe LH and FSH … Lutropin Alfa
When it comes to human sex hormones, estrogens, progestins, and testosterone are most often mentioned first. However, in addition to these, there is the group of gonadotropins, proteohormones that have an equally crucial influence on ovaries, testes and endocrine functions. This group of hormones includes, for example, FSH, LH, prolactin, and hCG. What are gonadotropins? … Gonadotropins: Function & Diseases
