Products Opicapone was approved in the EU in 2016 and in many countries in 2018 in hard capsule form (Ongentys). Structure and properties Opicapone (C15H10Cl2N4O6, Mr = 413.2 g/mol) is an oxadiazole derivative with a pyridine–oxide at position 3. The compound was designed with the goal of developing an effective and safer COMT inhibitor. This … Opicapon
Definition Capsules are solid and single-dose dosage forms of medicine of various shapes and sizes, usually intended for ingestion. This article refers to hard capsules. Soft capsules are covered in a separate article. Hard capsules, unlike them, do not contain plasticizers. Capsules consist of a capsule shell and the filling material, which contains the active … Capsules
Products Silodosin has been approved in hard capsule form in the United States since 2008, in the EU since 2010, and in many countries since 2016 (Urorec). Generic versions are registered in some countries. Structure and properties Silodosin (C25H32F3N3O4, Mr = 495.5) exists as a white to yellowish powder that is sparingly soluble in water. … Silodosin
Products Pomalidomide is commercially available in the form of hard capsules (Imnovid). It has been approved in many countries since 2014. It has been registered in the EU and the United States since 2013. Structure and properties Pomalidomide (C13H11N3O4, Mr = 273.2 g/mol) is an amino derivative of thalidomide and a racemate. It is also … Pomalidomide
Products Ozanimod was approved in the United States and many countries in 2020 in hard capsule form (Zeposia). Structure and properties Ozanimod (C23H24N4O3, Mr = 404.5 g/mol) is present in the drug as ozanimod hydrochloride, a white solid that is highly soluble in water. Active metabolites are involved in the effects. Effects Ozanimod (ATC L04AA38) … Ozanimod
