The word comes from ancient Greek and means “hard skin”. Scleroderma is a rare inflammatory rheumatic disease from the group of collagenoses, which can take on mild and severe, life-threatening forms. The disease affects the small blood vessels and connective tissue. This is where collagen is deposited, which manifests itself as hardened skin foci. Scleroderma … Scleroderma
Frequency distribution The rate of new cases is 1-2 persons per 100. 000 per year. Usually the age at the onset of the disease is 40-60 years. The incidence of the disease in the population is less than 50 per 100,000. Women are affected by a factor of 4 more frequently than men. Symptoms of … Frequency distribution | Scleroderma
Course and prognosis The course of the disease is difficult to predict and cannot be deduced from the constellation of symptoms. It can happen that unforeseen, very serious courses occur, which lead to death within months. However, morphea is not life-threatening. Women generally have a better prognosis than men. In systemic scleroderma, the infestation of … Course and prognosis | Scleroderma
