Proton Pump Inhibitors

Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors

Rabeprazole

Products Rabeprazole is commercially available in the form of film-coated tablets (Pariet, generic). It has been approved in many countries since 1999. Generic versions have been available since 2012. Structure and properties Rabeprazole (C18H21N3O3S, Mr = 359.4 g/mol) is a benzimidazole and pyridine derivative and a racemate. It is present in drugs as rabeprazole sodium, … Rabeprazole

Ranitidine: Drug Effects, Side Effects, Dosage and Uses

Products Ranitidine was commercially available in the form of film-coated tablets, effervescent tablets, and as a solution for injection and had been approved since 1981 (Zantic, generic). Currently, drugs containing ranitidine are no longer available in many countries. Starting in 1996, tablets for self-medication with 75 mg were released. However, they are now also no … Ranitidine: Drug Effects, Side Effects, Dosage and Uses

H2 Receptor Antagonists

Products H2 receptor antagonists were commercially available in many countries in tablet, effervescent tablet, and solution for injection forms, among others. Currently, no more drugs are available. Due to proton pump inhibitors (PPI), H2 antagonists have become less important. The first active ingredient, cimetidine (Tagamet), was developed in the 1960s and 70s under the leadership … H2 Receptor Antagonists

Lansoprazole

Products Lansoprazole is commercially available in the form of capsules as meltable tablets (Agopton, generics). It has been approved in many countries since 1993. Structure and properties Lansoprazole (C16H14F3N3O2S, Mr = 369.4 g/mol) is a benzimidazole and pyridine derivative. It exists as a white to brownish-white, odorless, crystalline powder that is practically insoluble in water. … Lansoprazole