Sickle cell anemia (technical term: drepanocytosis) is a hereditary disease of red blood cells. A distinction is made between a severe homozygous and a mild heterozygous form. Because heterozygous sickle cell anemia confers a degree of resistance to malaria, it is prevalent primarily in malaria risk areas (Africa, Asia, and the Mediterranean region). What is … Sickle Cell Anemia: Causes, Symptoms & Treatment
Bilirubin encephalopathy is a severe complication of hyperbilirubinemia in the newborn. It involves damage to the central nervous system. Severe sequelae or even a fatal outcome are possible. What is bilirubin encephalopathy? Bilirubin encephalopathy is characterized by severe central nervous system (CNS) damage caused by elevated bilirubin levels in the neonatal period. Hyperbilirubinemia can cause … Bilirubin Encephalopathy: Causes, Symptoms & Treatment
Aplastic crisis refers to a condition of drastic deterioration in the formation of red blood cells (RBCs) in the setting of hemolytic anemia. The cause of this crisis is usually the coincidence of chronic hemolytic anemia with ringworm infection. Only blood transfusion can overcome this critical condition. What is an aplastic crisis? Aplastic crisis is … Aplastic Crisis: Causes, Symptoms & Treatment
Primaquine is a prescription drug with anti-parasitic properties. It is used for the prevention, treatment, and follow-up of malaria. In its guidelines for the treatment of malaria, the German Society for Tropical Medicine and International Health (DTG) recommends primaquine as an adjunctive therapy to chloroquine in the treatment of malaria tertiana. In Germany, primaquine is … Primaquine: Effects, Uses & Risks
Glycolysis involves biocatalytically controlled breakdown of simple sugars such as D-glucose in humans and in almost all multicellular organisms. The degradation and conversion process of glucose to pyruvate occurs in ten sequential steps and can occur under aerobic and anaerobic conditions alike. Glycolysis is used for energy production, and pyruvate provides an initial precursor for … Glycolysis: Function, Tasks, Role & Diseases
Course of disease Icterus is a symptom of an illness or, in the context of newborns, usually a naturally occurring phenomenon. The course of the “jaundice triggering” disease is basically decisive. Depending on the cause and therapeutic measures, the course of the icterus is also determined. Decisive for the existence of jaundice are increased concentrations … Course of disease | Jaundice
What is a kernicterus? Kerincterus is a severe damage to the child’s brain caused by abnormally high concentrations of bilirubin or indirect bilirubin. Indirect bilirubin has not yet been processed in the liver and, due to its special property, can cross the so-called blood–brain barrier. Various diseases can cause an unusually high increase in bilirubin … What is a kernicterus? | Jaundice
Synonyms Icterus Definition jaundice Jaundice is an unnatural yellowing of the skin or the conjunctiva of the eyes and the mucous membranes, which is caused by an increase in the metabolic product bilirubin. If the level of bilirubin in the body rises above 2 mg/dl, yellowing is triggered. What is an icterus? Icterus is the … Jaundice
Symptoms of jaundice The icterus is characterized by a coloration of the skin. Often the skin tone is described as yellowish, which is also reflected in the name of jaundice. If the total bilirubin rises above 2mg/dl in the serum, not only the skin but also the eyes can be affected by the coloration. This … Symptoms of jaundice | Jaundice
Frequency of jaundice The frequency of jaundice depends on the disease causing it. In hepatitis A, for example, less than 10% of children under 6 years of age have an icteric course, 45% of children over 6 years of age and 75% of adults. Hemolyticus neonatorum disease as the cause of jaundice (icterus) is relatively … Frequency of jaundice | Jaundice
Factor XI deficiency is a clotting disorder. Factor XI is a clotting factor, a part in the clotting cascade that in turn activates other parts, and its failure therefore affects the course of the entire clotting cascade. What is factor XI deficiency? Factor XI is a proenzyme of the serine protease factor XIa and plays … Factor XI Deficiency: Causes, Symptoms & Treatment
Stem cells are considered the precursors of somatic cells and can divide almost endlessly. A wide variety of cell types develop from them. What are stem cells? A stem cell is a body cell that does not yet have a function in the organism. For this reason, they have the ability to develop into a … Stem Cells: Structure, Function & Diseases
