Hypercholesterolemia: Definition, Symptoms

Brief overview Symptoms: Initially no symptoms, but in the long term possibly serious consequences such as vascular calcification. Treatment: Among other things, changes in lifestyle and dietary habits, drug treatment of high cholesterol levels and existing underlying diseases. Causes and risk factors: Among other things, high cholesterol diet, heredity, other underlying diseases or certain medications. … Hypercholesterolemia: Definition, Symptoms

Alirocumab: Effects, Uses & Risks

Alirocumab is an experimental drug for hypercholesterolemia. It is one of the monoclonal antibodies. Alirocumab was introduced in May 2013 at “Pharmacon Meran” by Austrian scientist Manfred Schubert-Zsilavecz. What is alirocumab? Alirocumab is an experimental drug for hypercholesterolemia. Alirocumab functions as an inhibitor (inhibitor) of the human enzyme proprotein convertase subtilisin/kexin type 9 – PCSK9 … Alirocumab: Effects, Uses & Risks

Letrozole

Products Letrozole is commercially available in the form of film-coated tablets (Femara, generic). It has been approved in many countries since 1997. Structure and properties Letrozole (C17H11N5, Mr = 285.3 g/mol) is a nonsteroidal aromatase inhibitor. It exists as a white to yellowish crystalline powder that is nearly odorless and virtually insoluble in water. Letrozole … Letrozole

Fenofibrate

Products Fenofibrate is commercially available in the form of capsules (lipanthyl). It has been approved in many countries since 1977. In 2014, a fixed combination with simvastatin was registered (Cholib); see Fenofibrate Simvastatin. Structure and properties Fenofibrate (C20H21ClO4, Mr = 360.8 g/mol) exists as a white crystalline powder that is practically insoluble in water. It … Fenofibrate

Cholesterol Ester Storage Disease: Causes, Symptoms & Treatment

Cholerstinester storage disease is a lysosomal storage disease and inborn error of metabolism with a genetic basis. The disease is hereditary and is caused by a genetic mutation in the coding genes for lysosomal acid lipase. Symptomatic treatment of patients is conservative medication or enzyme replacement therapy steps. What is cholesterol ester storage disease? The … Cholesterol Ester Storage Disease: Causes, Symptoms & Treatment

Glucosamine

Products Glucosamine is commercially available in capsule, tablet, and liquid forms, among others. Glucosamine has not yet been approved as a drug in many countries and is not reimbursed by basic insurance. This is in contrast to [chondroitin sulfate. Structure and properties D-glucosamine or 2-amino-2-deoxy-β-D-glucose (C6H13NO5, Mr = 179.17 g/mol) is an amino sugar that … Glucosamine

Colestyramine

Colestyramine is an active ingredient used in the treatment of hypercholesterolemia. Too high LDL cholesterol levels in the blood can increase the risk of arteriosclerosis and thus of heart attacks and similar diseases. Colestyramine binds the bile acids in the intestines and prevents their reabsorption into the body. As a result, the body needs more … Colestyramine

Side effect | Colestyramine

Side effect With increasing age and increasing dose, the frequency of side effects increases significantly. Constipation is particularly frequent, but is easily treatable in most patients and only a few of them stop treatment. In the gastrointestinal tract, diarrhoea, fatty stools, vomiting, bleeding, swallowing difficulties and intestinal obstruction can also occur. For most of the … Side effect | Colestyramine

Price | Colestyramine

Price The base price of colestyramine is around 60 to 80 cents per bag. A pack of 100 bags costs about 70 euros. The costs are usually covered by health insurance companies. Is cholestyramine available over the counter? In Germany, colestyramine is available only in pharmacies and only on prescription. You cannot therefore buy colestyramine … Price | Colestyramine

Fat metabolism

Definition Fat metabolism in general refers to the absorption, digestion and processing of fats. We absorb fats through food or build them up from precursors ourselves and use them, for example, to provide energy or to produce important messenger substances in the body. After carbohydrates, fats are the most important suppliers of energy for our … Fat metabolism

Fat metabolism disorder | Fat metabolism

Fat metabolism disorder Fat metabolism disorders are shifts in the values of blood lipids. These can be either increased or decreased. One must differentiate between altered values of lipids (triglycerides) and altered values of lipoproteins (transport form of fats in the blood). Accordingly, a shift in the lipid values can result in increased cholesterol and/or … Fat metabolism disorder | Fat metabolism