insulin pen

Diabetes Mellitus Type 1

Symptoms The possible acute symptoms of type 1 diabetes include: Thirst (polydipsia) and hunger (polyphagia). Increased urination (polyuria). Visual disturbances Weight loss Fatigue, exhaustion, declining performance. Poor wound healing, infectious diseases. Skin lesions, itching Acute complications: Hyperacidity (ketoacidosis), coma, hyperosmolar hyperglycemic syndrome. The disease usually manifests in childhood or adolescence and is therefore also called … Diabetes Mellitus Type 1

Insulin Degludec

Products Insulin degludec is commercially available as a solution for injection (Tresiba). It is also combined fixed with insulin aspart (Ryzodeg, see under IDegAsp). It was newly approved in many countries in March 2013. In 2014, a fixed combination with liraglutide was registered (Xultophy); see under IDegLira. Structure and properties Insulin degludec has essentially the … Insulin Degludec

Insulin Detemir

Products Insulin detemir is commercially available as an injectable (Levemir). It has been approved in many countries since 2003. Structure and properties Insulin detemir (C267H402O76N64S6, Mr = 5916.9 g/mol) has an identical primary sequence to human insulin except for the removed threonine at position B30 of the B chain and an added molecule of myristic … Insulin Detemir

Insulin Glargine

Products Insulin glargine is commercially available as an injectable (Lantus). It has been approved in many countries since 2002. The biosimilar Abasaglar (LY2963016) was approved in the EU in 2014 and in many countries in 2015. The drugs must be stored between 2 to 8°C in a refrigerator. In 2015, Toujeo was additionally approved in … Insulin Glargine

Insulin Glulisine

Products Insulin glulisine is commercially available as an injectable and is usually administered with an insulin pen (Apidra). It has been approved in many countries since 2005. The brand name Apidra is derived from English (fast), and the active ingredient name glulisine is derived from the exchanged amino acids glutamic acid and lysine. Structure and … Insulin Glulisine

Insulin Lispro

Products Insulin lispro is commercially available as an injectable (Humalog). It has been approved in many countries since 1995. Biosimilars are available in some countries. In 2021, Lyumjev was approved in many countries, a new formulation that is characterized by an (even) faster onset of action and a slightly shorter duration of action. Structure and … Insulin Lispro

Insulin Pen: Needle Use and Application

Most diabetics use what is called an insulin pen as part of their insulin therapy. These are about the size of a pen and allow for easy dosing of insulin units. To learn how to use the insulin pen correctly, whether it is possible to use insulin pen needles more than once, and what the … Insulin Pen: Needle Use and Application

Insulin Pen Needles: Needle Change Recommendation

As part of their insulin therapy, many diabetics wonder how often they need to change the needles in their insulin pen: After each use, or can the pen needles be used more than once? You can find all the information you need here. What do doctors and diabetes educators recommend about changing needles? Doctors and … Insulin Pen Needles: Needle Change Recommendation