Adonis

Stem plant Ranunculaceae, Adonis. Medicinal drug Adonidis herba, Adonis herb: The dried herb of L. collected at flowering time (PH 5) – no longer officinal. Ingredients Cardiac glycosides of the cardenolide type. Effects Positive inotropic Indications Heart failure, is not used phytotherapeutically in many countries In alternative medicine Contraindications Therapy with cardiac glycosides, hypokalemia. Adverse … Adonis

Docusate Sodium

Products Docusate sodium is commercially available in many countries in the form of soft capsules and as ear drops, among other products. It is not registered as a laxative in many countries. Structure and properties Docusate sodium (C20H37NaO7S, Mr = 444.6 g/mol) exists as white, hygroscopic, and waxy flakes or masses and is sparingly soluble … Docusate Sodium

Macrogol 3350

Products Macrogol 3350 is commercially available as a powder for making an oral solution (e.g., Transipeg, Movicol, generics). It is included in drugs in combination with salts (potassium chloride, sodium chloride, sodium hydrogen sulfate) but can also be administered without them (e.g., Chung et al., 2009). Macrogol 4000 is also commercially available without salts. In … Macrogol 3350

Macrogole

Products Macrogols are commercially available in many countries as powders, granules, and as drinking solutions. The agents are available with or without salts (electrolytes). They have been approved since the 1980s. This article refers to pharmaceuticals. Macrogols such as macrogol 400 are also used as pharmaceutical excipients. Structure and properties Macrogols are mixtures of linear … Macrogole

Enteric-Coated Tablets

Products Several drugs are commercially available as enteric-coated tablets. Listed below are active ingredients that are administered with this dosage form: Proton pump inhibitors such as pantoprazole and esomeprazole. Some painkillers, e.g., NSAIDs such as diclofenac Digestive enzymes: pancreatin Laxative: bisacodyl Salicylates: mesalazine, acetylsalicylic acid 100 mg. Structure and properties Enteric coated tablets belong to … Enteric-Coated Tablets

Prucalopride

Products Prucalopride is commercially available in the form of film-coated tablets (Resolor). It was approved in many countries and in the EU in 2010. Structure and properties Prucalopride (C18H26ClN3O3, Mr = 367.87 g/mol) is a dihydrobenzofurancarboxamide. It has structural similarities to the prokinetic cisapride (prepulside, out of commerce). Effects Prucalopride (ATC A03AE04) has enterokinetic properties, … Prucalopride

Lubiproston

Products Lubiprostone is commercially available in the form of soft capsules (Amitiza). It has been approved in many countries since 2009. Structure and properties Lubiprostone (C20H32F2O5, Mr = 390.46) is a white, odorless powder that is insoluble in water and soluble in ethanol and ether. It is a derivative of a metabolite of prostaglandin E1. … Lubiproston

PED (Paraffin-Emodela Duphalac)

Production PED: Paraffinum liquidum 1/3 Emodella substitute 1/3 Duphalac or Rudolac 1/3 Since Emodella is out of trade, a substitute solution is made with a rotten tree bark extract: Emodella substitute: Frangulae extractum liquidum (Hanseler). 64.8 Glycerol 85 % PhEur 90.0 Ethanolum 96 % non potabile PhEur 83.4 Natrii benzoas pulvis 0.9 Aqua purificata PhEur … PED (Paraffin-Emodela Duphalac)

Epsom Salt

Products Epsom salt is available as an open product in pharmacies and drugstores. Specialty retailers can order it from specialized suppliers such as Hänseler. Epsom salt, as Epsom salt is also known, originated in Epsom, a suburb of London. Structure and properties Epsom salt is magnesium sulfate heptahydrate (MgSO4 – 7 H2O, Mr = 246.5 … Epsom Salt

Glycosides: Effects, Uses & Risks

Glycosides are organic or synthetic substances that result from the reversible condensation of two or more ring-shaped sugars or from the condensation of a sugar with a wide variety of alcohols via a so-called glycosidic bond, in each case splitting off an H2O molecule. Glycosides are synthesized by many plants in an almost incalculable variety, … Glycosides: Effects, Uses & Risks

Magnesium Deficiency

Symptoms Possible symptoms of clinically manifest magnesium deficiency include: Neuromuscular symptoms such as a tremor, muscle spasms, fasciculations (involuntary muscle movements), seizures Central disorders: Apathy, fatigue, dizziness, delirium, coma. Cardiovascular disorders: ECG changes, cardiac arrhythmias, palpable heartbeats, hypertension. Osteoporosis, Altered glucose homeostasis. Magnesium deficiency is often accompanied by calcium and potassium deficiency. However, many patients … Magnesium Deficiency