Lepirudin

Products Lepirudin was commercially available as a lyophilizate (Refludan). It was approved in many countries in 1997 and is no longer on the market. Structure and properties Lepirudin is a derivative of hirudin from the leech. Effects Lepirudin (ATC B01AX03) is anticoagulant by direct inhibition of thrombin. Indications Heparin-associated thrombocytopenia (HAT) type II.