Products
Lepirudin was commercially available as a lyophilizate (Refludan). It was approved in many countries in 1997 and is no longer on the market.
Structure and properties
Lepirudin is a derivative of hirudin from the leech.
Effects
Lepirudin (ATC B01AX03) is anticoagulant by direct inhibition of thrombin.
Indications
Heparin-associated thrombocytopenia (HAT) type II.
