Oxazolidinones

Effects Oxazolidinones have antibacterial activity against aerobic Gram-positive bacteria and anaerobic microorganisms. They bind to bacterial ribosomes and prevent the formation of a functional 70S initiation complex, and thus an essential step during the translation process. Indications For the treatment of bacterial infectious diseases. Active ingredients Linezolid (Zyvoxide) Tedizolid (Sivextro)

Rivaroxaban

Products Rivaroxaban is commercially available in the form of film-coated tablets (Xarelto, Xarelto vascular). It was approved in 2008 as the first agent in the direct factor Xa inhibitor group. Low-dose Xarelto vascular, 2.5 mg, was registered in many countries in 2019. Structure and properties Rivaroxaban (C19H18ClN3O5S, Mr = 435.9 g/mol) is a pure -enantiomer … Rivaroxaban

Linezolid

Products Linezolid is commercially available as an infusion solution, in the form of film-coated tablets, and as granules for preparation of a suspension (Zyvoxid, generics). It has been approved in many countries since 2001. Structure and properties Linezolid (C16H20FN3O4, Mr = 337.3 g/mol) was the first agent developed from the oxazolidinone group. It is structurally … Linezolid

Linezolid: Effects, Uses & Risks

Linezolid is an antibiotic from the oxazolidinone class of drugs. The drug is used as a reserve antibiotic. What is linezolid? Currently, linezolid is the only MRSA-active antibiotic available for both oral and intravenous use. The drug linezolid belongs to the fairly new group of oxazolidinones. Oxazolidinones have saturated heterocyclic compounds. They inhibit protein biosynthesis … Linezolid: Effects, Uses & Risks

Antibiotics: Antibacterial Drugs

Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs

Tedizolid

Products Tedizolid is commercially available as an infusion preparation and in tablet form (Sivextro). It was approved in the United States in 2014 and in many countries and the EU in 2015. Structure and properties Tedizolid (C17H15FN6O3, Mr = 370.3 g/mol) is present in the drug in the form of the prodrug tedizolid phosphate, a … Tedizolid

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment

Black Hair Tongue

Symptoms In black hairy tongue, a colored, hairy coating appears on the middle and back portions of the tongue. The discoloration can be black, gray, green, brown, and yellow. Itching, burning of the tongue, bad breath, changes in taste, metallic taste, nausea and lack of appetite are other possible symptoms. When swallowed, the “hairs” may … Black Hair Tongue