mitoxantrone

Anthranoid

Definition Plant antraceene derivatives with the common structural feature 1,8-dihydroxyanthrone. Numerous derivatives (anthrones, anthranols, anthraquinones, dianthrones, naphthodianthrones). 1,8-Dihydroxyanthrone: Effects Laxative (Prodrugs) Antidepressant: St. John’s wort Antiarthrotic: Rhine, Diacerein (Verbonil). Cytotoxic: mitoxantrone (Novantrone). Indications Primarily for short-term treatment of constipation. Bowel emptying Some: Osteoarthritis Medicinal drugs Aloe: e.g. aloin A American rotten tree (Cascara bark) Sloth … Anthranoid

Multiple Sclerosis Causes and Treatment

Symptoms Possible symptoms of multiple sclerosis include: Weakness, numbness of the extremities. Visual disturbances, eye pain, optic neuritis. Paresthesias (eg, formication, tingling), pain, nerve pain. Tremor, coordination / balance disorders. Speech and swallowing disorders Dizziness, lightheadedness Fatigue Urinary incontinence, constipation Sexual function disorders, erectile dysfunction The disease is often relapsing and recurrent (relapsing-remitting multiple sclerosis), … Multiple Sclerosis Causes and Treatment

Mitoxantrone

Products Mitoxantrone is commercially available as an infusion/injection solution (Novantrone, generic). It has been approved in many countries since 1985. Structure and properties Mitoxantrone (C22H28N4O6, Mr = 444.5 g/mol) Effects Mitoxantrone (ATC L01DB07) has cytotoxic and immunosuppressive properties. The effects are due to inhibition of topoisomerase II and intercalation of DNA. Indications Carcinomas, lymphomas, leukemia … Mitoxantrone

Change in Urine Color

Symptoms A change in urine color is manifested by a deviation from the normal color of urine, which usually varies from pale yellow to amber. It may occur as a solitary sign or along with other symptoms. Urine is usually clear and not cloudy. It gets its color from urine pigments called urochromes. These are, … Change in Urine Color

Immunosuppressants

Products Immunosuppressants are commercially available in numerous dosage forms, for example, as creams, ointments, tablets, capsules, solutions, eye drops, and injectables. Structure and properties Within immunosuppressants, several groups can be identified. These include steroids such as the glucocorticoids, substances of microbiological origin such as ciclosporin and mycophenolate mofetil, derivatives of nucleic acids and their components … Immunosuppressants

Mitoxantrone: Effects, Uses & Risks

The drug mitoxantrone belongs to the group of cytostatic drugs. The drug is administered to treat cancer as well as multiple sclerosis. What is mitoxantrone? The cytostatic drug mitoxantrone belongs to the anthracenidione group. It is used to treat malignant cancer and multiple sclerosis. In medicine, the active ingredient also goes by the names mitoxantrone … Mitoxantrone: Effects, Uses & Risks