Small Interfering RNA (siRNA)

Structure and properties Small interfering RNA (siRNA) is a short, synthetically produced RNA fragments consisting of approximately 21 to 25 nucleotides. The siRNA has a complementary sequence to a target mRNA in the human body and is usually administered in double-stranded form. Effects The sequence-specific siRNA leads to selective degradation of the complementary mRNA in … Small Interfering RNA (siRNA)

MRNA-1273

Products mRNA-1273 enters the market as a white dispersion in multidose containers. It was licensed in the EU on January 6, 2021, and in many countries on January 12, 2021. The vaccine has been studied in a clinical trial involving more than 30,000 participants. The unopened multi-dose vial can be stored at -15 °C to … MRNA-1273

MRNA Vaccines

Products mRNA vaccines are commercially available as injectables. The first in this group to be approved in many countries was BNT162b2 from BioNTech and Pfizer on December 19, 2020. Moderna’s mRNA-1273 is also an mRNA vaccine. It was released in the EU on January 6, 2021. Both are covid-19 vaccines. Structure and properties mRNA (short … MRNA Vaccines

COVID-19 Vaccines

Products Covid-19 vaccines are in the development and approval phase and are already available in some countries. In many countries, BNT162b2 was the first agent approved on December 19, 2020. mRNA-1273 was approved in the EU on January 6, 2021, and in many countries on January 12, 2021. The first approval will be in Russia … COVID-19 Vaccines

BNT162b2 (Tozinameran)

Products BNT162b2 from German biotechnology company BioNTech and Pfizer was approved in many countries on December 19, 2020, as the first representative of mRNA vaccines and Covid-19 vaccines (Comirnaty, frozen suspension). The vaccine was studied in 2020 in a large Phase III trial with more than 44,000 participants. Switzerland was the first country in which … BNT162b2 (Tozinameran)

Vaccines

Products Vaccines are mainly sold as injectables. Some are also taken perorally as oral vaccines, for example, in the form of capsules (typhoid vaccine) or as a suspension for oral administration (rotavirus). Monopreparations and combination preparations are commercially available. Vaccines, with few exceptions, are stored in a refrigerator at a temperature of 2 to 8 … Vaccines