Products Methotrexate is commercially available as a solution for parenteral use and in tablet form. See also under methotrexate prefilled syringe (low-dose). Structure and properties Methotrexate (C20H22N8O5, Mr = 454.44 g/mol) is a dicarboxylic acid that exists as a yellow to orange crystalline powder that is virtually insoluble in water. Methotrexate was developed as a … Methotrexate: Drug Effects, Side Effects, Dosage and Uses
Introduction – What is Ciclosporin A? Ciclosporin A is an immunosuppressive agent, i.e. a substance that suppresses the immune system and thus downregulates an immune response. For example, Ciclosporin A can be used after transplantation of different organs to prevent the body’s immune system from attacking the foreign organ (transplant). Ciclosporin A is also used … Ciclosporin A
Active ingredient and effect Ciclosporin A is an active ingredient of the immunosuppressive group. By means of a complex mechanism of action, Ciclosporin prevents the formation of so-called cytokines (proteins required for an immune reaction in the body). In addition, Ciclosporin A has an effect on lymphocytes, an important group of cells that are also … Active ingredient and effect | Ciclosporin A
Eye drops with Ciclosporin A Eye drops with Ciclosporin A are used for severe inflammation of the eyes. Ciclosporin reduces the immune response in the eye, producing fewer inflammatory substances and thus reducing potential eye damage. For particularly severe inflammation of the cornea with dry eyes, these eye drops are considered the first choice. Ciclosporin … Eye drops with Ciclosporin A | Ciclosporin A
How much does Ciclosporin A cost? In most cases, the costs for a therapy with Ciclosporin A are covered by health insurance or private health insurance. The drug should only be used if there is a medical indication, in which case the health insurance companies are obliged to pay the costs. Depending on the dosage … How much does Ciclosporin A cost? | Ciclosporin A
What should be considered when discontinuing immunosuppressive drugs? Immunosuppressive drugs are often taken over very long periods of time. Organ transplanted patients must take immunosuppressive drugs throughout their lives to avoid rejection after years. Due to the severe side effects of immunosuppressive drugs, many patients are unwilling to take the medication. In the worst case, … What should be considered when discontinuing immunosuppressive drugs? | Immunosuppressive drugs
Immunosuppressants for the treatment of Crohn’s disease Crohn’s disease is a chronic inflammatory disease that can affect the entire gastrointestinal tract. The following immunosuppressive drugs are used to treat an acute attack: Budesonide, mesalazine and possibly prednisolone. Budesonide is a glucocorticoid that is metabolised to a large extent in the liver. It therefore has mainly … Immunosuppressants for the treatment of Crohn’s disease | Immunosuppressive drugs
Immunosuppressive drugs for the treatment of multiple sclerosis Multiple sclerosis is an inflammatory, autoimmune nerve disease in the course of which the protective layer around the nerve fibers (myelin layer) is increasingly destroyed. MS progresses in phases, i.e. intervals of almost complete freedom from pain alternate with strong attacks of the disease. Especially during the … Immunosuppressive drugs for the treatment of multiple sclerosis | Immunosuppressive drugs
ExplanationDefinition Methotrexate is a long-term disease-modifying antirheumatic drug (DMARD), a basic therapeutic agent in the treatment of rheumatoid arthritis and psoriatic arthritis. It is used in cases of high disease activity. In case of ineffectiveness or decreasing effectiveness, methotrexate can be combined with other DMARDs. In therapy with methotrexate, undesirable side effects can be counteracted … Methotrexate
Side effects The side effects depend on the dosage and the duration of use of Methotrexate (e.g. LantarelMetexMTX). They may occur during the entire period of use, but are most common in the first six months. Only the frequently and occasionally occurring side effects are listed here; rare, very rare or isolated side effects are … Side effects | Methotrexate
Prescription requirement All dosages are available only on prescription! Methotrexate for rheumatism Methotrexate (MTX for short, trade name Lantarel®) is a drug that is very often used as a so-called anti-inflammatory drug for the treatment of rheumatic inflammation. The terms “rheumatism” or diseases of the rheumatic group of forms summarize hundreds of different diseases caused … Prescription requirement | Methotrexate
Methotrexate and folic acid Methotrexate is an active substance that acts as an antagonist of folic acid in the body (a so-called folic acid antagonist). Folic acid or vitamin B9 is important for cell division, in particular it plays a role in the production of building blocks of the genetic material (DNA). So if the … Methotrexate and folic acid | Methotrexate
