Zolmitriptan

Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan

Entacapon

Products Entacapone was commercially available in the form of film-coated tablets (Comtan). It was approved in many countries since 1999. In 2017, distribution was discontinued. A fixed combination with levodopa and carbidopa has also been available since 2004 (Stalevo). Generic versions of the combination drug were approved in 2014. Structure and properties Entacapone (C14H15N3O5, Mr … Entacapon

ACE Inhibitors List, Effects, Side Effects

Products Most ACE inhibitors are commercially available in the form of tablets and film-coated tablets. The first agent from this group to be approved was captopril, in many countries in 1980. ACE inhibitors are often combined with the thiazide diuretic hydrochlorothiazide (HCT) fix. Structure and properties ACE inhibitors are peptidomimetics derived from peptides found in … ACE Inhibitors List, Effects, Side Effects

Reteplase

Products Reteplase was marketed as an injectable (Rapilysin). The drug was approved in many countries in 1996 and withdrawn from the market in 2013. Structure and properties Reteplase is derivative of tissue-specific plasminogen activator (t-PA). It is a serine protease containing 355 of the 527 amino acids of native t-PA. The protein is produced by … Reteplase

Diabetes Mellitus Type 1

Symptoms The possible acute symptoms of type 1 diabetes include: Thirst (polydipsia) and hunger (polyphagia). Increased urination (polyuria). Visual disturbances Weight loss Fatigue, exhaustion, declining performance. Poor wound healing, infectious diseases. Skin lesions, itching Acute complications: Hyperacidity (ketoacidosis), coma, hyperosmolar hyperglycemic syndrome. The disease usually manifests in childhood or adolescence and is therefore also called … Diabetes Mellitus Type 1

Diabetes Mellitus Type 2: Causes and Treatment

Symptoms The possible acute symptoms of type 2 diabetes include: Thirst (polydipsia) and hunger (polyphagia). Increased urination (polyuria). Visual disturbances Weight loss Fatigue, exhaustion, declining performance. Poor wound healing, infectious diseases. Skin lesions, itching Acute complications: Hyperacidity (ketoacidosis), hyperosmolar hyperglycemic syndrome. Untreated diabetes is far from harmless and can lead in the longer term to … Diabetes Mellitus Type 2: Causes and Treatment

Meldonium

Products Meldonium is on the market mainly in Eastern European countries and states of the former Soviet Union in the form of capsules and as an injectable, for example in Russia, Belarus, Ukraine, and Latvia (Mildronate). However, it is not registered in many countries, in the EU and in the USA. Meldonium was developed in … Meldonium

Melitracene and Flupentixol

Products The fixed combination Deanxit with the two active ingredients melitracene and flupentixol is commercially available in many countries in the form of film-coated tablets. The drug has been approved since 1973, initially as dragées. The marketing authorization holder is the Danish company Lundbeck. Structure and properties The active ingredients are present in the drug … Melitracene and Flupentixol

Cyclobenzaprine

Products Cyclobenzaprine is commercially available in the United States and elsewhere in the form of film-coated tablets. No finished drug products containing cyclobenzaprine are currently registered in many countries. Structure and properties Cyclobenzaprine (C20H21N, Mr = 275.4 g/mol) is present in drugs as cyclobenzaprine hydrochloride, a white crystalline powder that is soluble in water. It … Cyclobenzaprine

Treatment Adherence

Definitions Treatment adherence refers to the extent to which a person’s behavior conforms to the agreed-upon recommendations of a health care professional or therapist. So, for example, with regard to taking medications, following a diet, or adhering to lifestyle changes. The English terms adherence and compliance are often used. Today, the term adherence is in … Treatment Adherence

Beta Blocker Effects and Side Effects

Products Beta-blockers are available in many countries in the form of tablets, film-coated tablets, sustained-release tablets, as capsules, solution, eye drops, and as injection and infusion solutions. Propranolol (Inderal) was the first representative of this group to appear on the market in the mid-1960s. Today, the most important active ingredients include atenolol, bisoprolol, metoprolol and … Beta Blocker Effects and Side Effects

Heart Attack: Signs and Symptoms

With a heart attack (myocardial infarction) almost everyone has already come into contact. Be it as a sufferer or as an acquaintance of someone affected by a heart attack. If our circulatory motor lacks oxygen, it starts to stutter or stops completely. This does not happen so rarely: More than 220,000 people suffer a heart … Heart Attack: Signs and Symptoms