Products Suvorexant was approved in the United States in 2014 as the first agent in the orexin receptor antagonist group in the form of film-coated tablets (Belsomra). Structure and properties Suvorexant (C23H23ClN6O2, Mr = 450.9 g/mol) exists as a white powder that is insoluble in water. It is a benzoxazole, diazepane and triazole derivative. Effects … Suvorexant
Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)
Products Dexmethylphenidate is commercially available in the form of capsules with a modified release of active ingredient (Focalin XR). It was approved in many countries in 2009. Since it does not contain L-threo-methylphenidate, the strengths are correspondingly half less (5 mg, 10 mg, 15 mg, 20 mg) than Ritalin LA (10 mg, 20 mg, 30 … Dexmethylphenidate
Products Dextromethorphan is available in the form of tablets, lozenges, sustained-release capsules, syrup, and drops, among others (in many countries, for example, Bexin, Calmerphan, Calmesin, Pulmofor, combination preparations). The first drugs came on the market in the 1950s. Structure and properties Dextromethorphan (C18H25NO, Mr = 271.4 g/mol) was developed as an analog of codeine and … Dextromethorphan
Products Dextromoramide is registered as a solution for injection for dogs (Palfivet, off label). It has been approved in many countries since 1960. Human drugs are not available in many countries. Structure and properties Dextromoramide (C25H32N2O2, Mr = 392.5 g/mol) is a diphenylpropylamine structurally similar to methadone. Effects Dextromoramide (ATCvet QN02AC01) is analgesic and has … Dextromoramide
Products AH-7921 is not on the market as a drug. It has been semi-legally and illegally traded on the black market and abused as an intoxicant since 2012. AH-7921 was patented in 1976 by Allen and Hanburys Ltd. Structure and properties AH-7921 (C16H22Cl2N2O, Mr = 329.3 g/mol) is structurally different from classical opioids such as … AH-7921
Products MDA is one of the narcotics and banned substances in many countries. It is not commercially available. MDA was first synthesized in 1910. Structure and properties Methylenedioxyamphetamine (C10H13NO2, Mr = 179.2 g/mol) is a 3,4-methylenedioxy derivative of amphetamine. It is structurally closely related to ecstasy (methylenedioxymethamphetamine, MDMA). Some ecstasy tablets contain MDA instead of … MDA (Methylenedioxyamphetamine)
Shisha smoking Shisha smoking involves heating tobacco with charcoal. It is referred to as smoldering. The smoke is passed through water and travels through a hose to the mouthpiece, which is used to inhale it. It is mostly smoked in shisha bars or cafes in a social setting. Many varieties exist and electric hookahs are … Shisha
Products In many countries, there are no drugs containing carisoprodol on the market. In other countries, it is available in tablet form (Soma, Somadril). It has been approved in the United States since 1959. In 2007, the European Medicines Agency concluded that the benefits of the drug did not outweigh the risks. Structure and properties … Carisoprodol
Products Cyclobenzaprine is commercially available in the United States and elsewhere in the form of film-coated tablets. No finished drug products containing cyclobenzaprine are currently registered in many countries. Structure and properties Cyclobenzaprine (C20H21N, Mr = 275.4 g/mol) is present in drugs as cyclobenzaprine hydrochloride, a white crystalline powder that is soluble in water. It … Cyclobenzaprine
Products Thiopental is commercially available as an injectable (generic). It has been approved in many countries since 1947. Structure and properties Thiopental (C11H18N2O2S, Mr = 242.3 g/mol) is present in the drug as thiopental sodium, a yellowish white, hygroscopic powder that is readily soluble in water. It is a lipophilic thiobarbiturate identical to pentobarbital except … Thiopental
Periradicular therapy (PRT) is an injection used to treat pain around the nerve roots of the spine. Back pain is common and often chronic. Here, PRT promises a pain-relieving or pain-relieving option, depending on the cause of the back pain. What is periradicular therapy? Periradicular therapy involves using an imaging procedure – usually CT – … Periradicular Therapy: Treatment, Effects & Risks
