Products In many countries, no drugs containing carfentanil are on the market. The active ingredient is used in veterinary medicine (Wildnil). Legally, it belongs to narcotics. Structure and properties Carfentanil (C24H30N2O3, Mr = 394.5 g/mol) is structurally closely related to fentanyl, being 4-methoxycarbonylfentanyl. Carfentanil citrate is present in pharmaceuticals. The active ingredient was developed at … Carfentanil
The drug prochlorperazine is used in human medicine primarily as a medication for nausea, vomiting, and migraine. Occasionally, the dopamine antagonist is also prescribed to treat psychiatric or mental illness. Accordingly, prochlorperazine is both an antiemetic and a neuroleptic. What is prochlorperazine? The active medical ingredient prochlorperazine belongs to the group of antiemetics. This term … Prochlorperazine: Effects, Uses & Risks
Products Lisdexamphetamine (LDX) was approved in many countries in March 2014 in capsule form (Elvanse). It has been available in the United States since 2007 (Vyvanse). The dosage form is non-retarded, unlike other ADHD medications. Continuous release is achieved with the conversion of the prodrug. Lisdexamphetamine is legally classified as a narcotic and therefore requires … Lisdexamphetamine
Products In many countries, drugs containing butalbital are no longer approved (e.g., Cafergot-PB). Combination products are still on the market in some countries, including the United States, where numerous products are available. Structure and properties Butalbital (C11H16N2O3, Mr = 224.3 g/mol) or 5-allyl-5-isobutylbarbituric acid exists as a slightly bitter, white, odorless, crystalline powder that is … Butalbital
Products Butamirate is commercially available as a syrup, drops, and depot tablets (e.g., NeoCitran cough suppressant, formerly Sinecod). It has been approved in many countries since 1965. Structure and properties Butamirate (C18H29NO3, Mr = 307.4 g/mol) is present in drugs as butamirate dihydrogen citrate. It has structural similarities to the antitussive butetamate. Butamirate is not … Butamirate
Products Pregabalin is commercially available in capsule form and as an oral solution (Lyrica, generics). It was approved in the United States and EU in 2004 and in many countries in 2005. Structure and properties Pregabalin (C8H17NO2, Mr = 159.2 g/mol) exists as a white crystalline powder that is soluble in water. It was developed … Pregabalin
Structure and properties Cocaethylene (C18H23NO4, Mr = 317.4 g/mol) is a derivative of cocaine. Unlike cocaine, it contains an ethyl ester rather than a methyl ester. Formation Cocaethylene is formed when cocaine and ethanol are consumed simultaneously in the liver by a process called transesterification. The reaction occurs during catalysis by carboxylesterase 1 (hCE1). This … Cocaethylene
Products In many countries, finished medicines containing cocaine are currently no longer commercially available. However, they can be prepared as an extemporaneous prescription in a pharmacy. Cocaine is subject to the Narcotics Act and requires an aggravated prescription, but it is not banned as a drug. It is also sold as an illegal narcotic on … Cocaine: Drug Effects, Side Effects, Dosage and Uses
Products Dimetinden maleate is available as oral drops (Feniallerg drops). They were formerly called Fenistil drops. The drug has been approved in many countries since 1961. Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is … Dimetinden Maleate Drops
Products In many countries, no medicines containing preparations of angel’s trumpet are on the market. Angel’s trumpets are sold as ornamental plants. Stem plant Angel’s trumpets belong to the genus and family Solanaceae. Representatives are, for example , and . The decorative plants are originally from South America. They are perennial shrubs or trees with … Angel Trumpets
Products Antitussives are commercially available in the form of tablets, capsules, as cough syrups, and drops, among others. Structure and properties Antitussives do not have a uniform chemical structure. However, many are derived from natural opium alkaloids (opioids). Effects Antitussives have cough-irritating (antitussive) properties. They reduce the frequency and intensity of coughing attacks. Their effects … Antitussives
Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses
