Products Dihydropyridines are commercially available in many countries in the form of film-coated tablets, sustained-release tablets, capsules, and injectables. Nifedipine from Bayer (Adalat) was the first active ingredient from this group to enter the market in the mid-1970s. Today, amlodipine (Norvasc, generics) is most commonly prescribed. Structure and properties The name 1,4-dihydropyridines is derived from … Dihydropyridine
Products Diltiazem ointments are not registered as finished drug products in many countries. However, they can be prepared as an extemporaneous prescription in a pharmacy. Typically, two-percent dosage forms are used (gel, cream, or ointment). There are various manufacturing instructions. For example, white petroleum jelly, Excipial oily ointment, DAC base cream, or a gel base … Diltiazem Ointment
Products Nifedipine is commercially available in the form of sustained-release tablets (generics). It was first approved in the mid-1970s. Sales of the original Adalat were discontinued in many countries in 2019. Structure and properties Nifedipine (C17H18N2O6, Mr = 346.3 g/mol) is a dihydropyridine. It exists as a yellow crystalline powder that is practically insoluble in … Nifedipine: Drug Effects, Side Effects, Dosage and Uses
Effects Nifedipine is an active ingredient of the dihydropyridine group and has a relaxing effect on vascular smooth muscle. When used topically or orally, it dilates blood vessels, improves blood flow and thus wound healing, is anti-inflammatory, and relieves anal sphincter spasms. Dihydropyridines inhibit the influx of calcium into smooth muscle cells by inhibiting L-type … Nifedipine Cream for Anal Fissure
Symptoms Anal fissure is a tear or cut in the skin of the anal canal. This results in severe pain that occurs during and up to several hours after defecation. It may radiate locally and be accompanied by an uncomfortable itching sensation. Fresh blood can often be seen on toilet paper or stool. Causes Possible … Anal Fissure: Symptoms, Diagnosis, Causes and Treatment
Definition Most drugs today are pre-produced in large quantities and enter the market ready for use. However, drugs also exist that are produced in the laboratory by pharmacies on a doctor’s prescription for individual customers. These are referred to as extemporaneous preparations. The following is the definition according to the Federal Law on Medicinal Products … Magisterial Recipes
Products Rectogesic ointment is approved in many countries (some countries: Rectiv). Nitroglycerin ointments are also used in a higher concentration for transdermal treatment of angina (2%). This article refers to rectal administration for anal fissure. Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is nitrated glycerol. Pure nitroglycerin is explosive and … Nitroglycerin Ointment
The term anal fissure describes a tear in the mucosa of the anus. This usually causes severe pain and is mainly caused by strong pressing during bowel movements. In the acute form, conservative treatment is usually sufficient and surgery is not necessary. There are numerous ointments and creams that support the regeneration of the anal … Anal fissure – Cream
Ointment for children In children, anal fissures occur significantly less often than in adults. As a rule, there are only one or more small tears in the mucosa, but these usually heal within a few days before a fissure develops. Therefore, a restrained treatment is usually preferred at first. This includes stool-softening measures, such as … Ointment for children | Anal fissure – Cream
