Opipramol: Effects, Application, Side Effects

How opipramol works Opipramol is a tricyclic antidepressant and has a calming, anxiety-relieving and slightly mood-lifting effect. Unlike conventional antidepressants, however, this effect is not based on inhibiting the reuptake of neurotransmitters in the brain (such as serotonin or norepinephrine). Instead, strong binding to specific binding sites in the brain (including sigma-1 receptors) has been … Opipramol: Effects, Application, Side Effects

Opipramol: Effects, Dosage, Side Effects

Opipramol is an anti-anxiety and sedative medication with a low dependence potential that is often prescribed to treat anxiety. However, side effects can still occur when taking opipramol, and they are not insignificant. The chemical structure of the active ingredient opipramol is similar to the group of tricyclic antidepressants. However, it primarily has an antianxiety … Opipramol: Effects, Dosage, Side Effects

Anxiolytics

Products Anxiolytics are commercially available in the form of tablets, capsules, and injectable preparations, among others. Structure and properties Anxiolytics are a structurally heterogeneous group. However, the representatives can be divided into different classes. These include, for example, the benzodiazepines or the tricyclic antidepressants. Effects Anxiolytics have antianxiety (anxiolytic) properties. They usually have additional effects, … Anxiolytics

Tricyclic Antidepressants

Products Tricyclic antidepressants are commercially available in many countries in the form of dragées, tablets, capsules, and drops. The first representative, imipramine, was developed at Geigy in Basel. Its antidepressant properties were discovered in the 1950s by Roland Kuhn at the psychiatric clinic in Münsterlingen (Thurgau). Imipramine was approved in many countries in 1958. Structure … Tricyclic Antidepressants

Insidon®

Definition The drug Insidon® is a drug from the group of psychotropic drugs. Insidon® is a drug name, the active ingredient is opipramol. Insidon® is prescribed in particular for anxiety disorders and somatoform disorders (these are diseases in which no cause for certain physical symptoms can be found and where psychosocial factors play an important … Insidon®

Contraindications | Insidon®

Contraindications Patients suffering from certain diseases should not take Insidon® or only after consultation with their doctor. This applies to: Insidon® should not be used during pregnancy and lactation. Especially in the first trimester of pregnancy other preparations should be used. If it is necessary to take Insidon® while breastfeeding, the woman should stop breastfeeding, … Contraindications | Insidon®

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment

Opipramol

Products Opipramol is commercially available in the form of dragées (Insidon). It has been approved in many countries since 1961, originally by Geigy, later by Novartis. Structure and properties Opipramol (C23H29N3O, Mr = 363.5 g/mol) structurally belongs to the tricyclic antidepressants and is a dibenzazepine derivative. It is present in the drug as opipramol dihydrochloride. … Opipramol