parasympatholytics

Cystic Fibrosis: Causes and Treatment

Symptoms In cystic fibrosis (CF, cystic fibrosis), different organ systems are affected, resulting in a heterogeneous clinical picture with symptoms of varying severity: Lower respiratory tract: Chronic cough with viscous mucus formation, obstruction, recurrent infectious diseases, e.g., with , inflammation, remodeling of the lungs (fibrosis), pneumothorax, respiratory insufficiency, shortness of breath, wheezing, oxygen deficiency. Upper … Cystic Fibrosis: Causes and Treatment

Rivastigmine

Products Rivastigmine is commercially available as capsules, oral solution, and transdermal patch (Exelon, generics). It has been approved in many countries since 1997. Structure and properties Rivastigmine (C14H22N2O2, Mr = 250.3 g/mol) is a phenyl carbamate. It exists in the oral forms as rivastigmine hydrogenotartrate, a white crystalline powder that is very soluble in water. … Rivastigmine

Mirabegron

Products Mirabegron is commercially available in the form of sustained-release film-coated tablets (Betmiga, USA: Myrbetriq). It was approved in the US and EU in 2012 and in many countries in 2014. Mirabegron was the first agent from the beta3 agonist group to be approved for the treatment of irritable bladder. It was originally intended to … Mirabegron

Datura: Medicinal Uses

Products Datura extracts are hardly used pharmaceutically today. Alternative medicine preparations such as homeopathics and the pure ingredients such as atropine and scopolamine are an exception. Stem plant Datura L. of the nightshade family (Solanaceae). Medicinal drug Stramonium leaves (Stramonii folium) are used as a medicinal raw material, the dried leaves or from the dried … Datura: Medicinal Uses

Biperides

Products Biperiden is commercially available as tablets, sustained-release tablets, and a solution for injection (Akineton, Akineton retard). It has been approved in many countries since 1958. Structure and properties Biperiden (C21H29NO, Mr = 311.46 g/mol) is present in drugs as biperidene hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a … Biperides

Revefenacin

Products Revefenacin was approved in the United States in 2018 as a monodose inhalation solution (Yupelri). The active ingredient belongs to the LAMA group. Structure and properties Revefenacin (C35H43N5O4, Mr = 597.8 g/mol) exists as a white crystalline powder and is sparingly soluble in water. It has an active metabolite formed by hydrolysis. Effects Revefenacin … Revefenacin

Solifenacin

Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin

Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Propiverine

Products Propiverine was approved in many countries in 2020 in the form of modified-release hard capsules (Mictonorm). Later, coated tablets were also registered (Mictonet). This is an older active ingredient that was available earlier in Germany, for example. Structure and properties Propiverine (C23H29NO3, Mr = 367.5 g/mol) is present in drugs as propiverine hydrochloride. Active … Propiverine

Multiple Sclerosis Causes and Treatment

Symptoms Possible symptoms of multiple sclerosis include: Weakness, numbness of the extremities. Visual disturbances, eye pain, optic neuritis. Paresthesias (eg, formication, tingling), pain, nerve pain. Tremor, coordination / balance disorders. Speech and swallowing disorders Dizziness, lightheadedness Fatigue Urinary incontinence, constipation Sexual function disorders, erectile dysfunction The disease is often relapsing and recurrent (relapsing-remitting multiple sclerosis), … Multiple Sclerosis Causes and Treatment

Darifenacin

Products Darifenacin is commercially available in the form of sustained-release tablets (Emselex). It has been approved in many countries since 2005. Structure and properties Darifenacin (C28H30N2O2, Mr = 426.6 g/mol) is a tertiary amine. It is present in drugs as darifenacin hydrobromide, a white crystalline powder. Effects Darifenacin (ATC G04BD10) has parasympatholytic properties. It is … Darifenacin

Angel Trumpets

Products In many countries, no medicines containing preparations of angel’s trumpet are on the market. Angel’s trumpets are sold as ornamental plants. Stem plant Angel’s trumpets belong to the genus and family Solanaceae. Representatives are, for example , and . The decorative plants are originally from South America. They are perennial shrubs or trees with … Angel Trumpets