prednisolone

Prednisolone: Effects, Uses, Side Effects

How does prednisolone work? Prednisolone inhibits inflammation, counteracts allergic reactions, and suppresses the body’s defenses (immunosuppression). Glucocorticoids such as prednisolone bind to so-called glucocorticoid receptors in the body. They are typically located inside the cell. After successful binding, the glucocorticoid-receptor complex enters the cell nucleus. There it influences the activity of various genes whose products … Prednisolone: Effects, Uses, Side Effects

Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Cortisone Tablets Effects and Side Effects

Products Cortisone tablets are medicinal products which are intended for ingestion and contain active substances from the group of glucocorticoids. The tablets, water-soluble tablets and sustained-release tablets are usually monopreparations, which are often divisible. Glucocorticoids were first used medicinally in the late 1940s. Structure and properties The glucocorticoids contained in the drugs are derived from … Cortisone Tablets Effects and Side Effects

Sulfonamides

Effect Antibacterial Bakeriostatic Antiparasitic against protozoa Mechanism of action Sulfonamides inhibit the synthesis of folic acid in microorganisms. They are structural analogues (antimetabolites) of the natural substrate p-aminobenzoic acid and competitively displace it. Trimethoprim, used in combination with sulfamethoxazole, has a synergistic effect. Indications Bacterial infectious diseases caused by: Streptococcus Pneumococcus Actinomycetes Nocardia, e.g. nocaridosis … Sulfonamides

Antiallergics

Products Anti-allergy medications are available in numerous dosage forms. These include tablets, capsules, solutions, suspensions, nasal sprays, eye drops, inhalation preparations, and injectables. Structure and properties Antiallergic drugs do not have a uniform chemical structure. However, several groups within the class can be identified (see below). Effects Antiallergic drugs have antiallergic, antiinflammatory, immunosuppressive, antihistamine, and … Antiallergics

Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Prednisolone: Drug Effects, Side Effects, Dosage and Uses

Products Prednisolone is commercially available as tablets, eye drops, eye ointment, cream, ointment, solution, foam, and suppositories (Pred Forte, Prednisolone Streuli, Premandol, Spiricort, Ultracortenol). Structure and properties Prednisone (C21H26O5, Mr = 358.434 g/mol) is the prodrug of prednisolone. Effects Prednisolone (ATC H02AB06) has anti-inflammatory, antiallergic, and immunosuppressive properties. Indications Inflammatory non-infectious skin diseases see under … Prednisolone: Drug Effects, Side Effects, Dosage and Uses

Prednisone

Products Prednisone is available in tablet form from several manufacturers (Prednisone Galepharm, Prednisone Axapharm, Prednisone Streuli). Lodotra sustained-release tablets were approved in 2011. Structure and properties Prednisone (C21H26O5, Mr = 358.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug of prednisolone. Effects Prednisolone (ATC A07EA03, ATC … Prednisone

Prednisolone

Prednisolone is an artificially produced active substance, which belongs to the group of glucocorticoids. This group is often summarized under the well-known name “cortisone“. In its effects and side effects, prednisolone is similar to the hormone cortisol or hydrocortisone, which is produced in the adrenal cortex of the human body. It can be used in … Prednisolone

Side Effects of Prednisolone

High doses of cortisone should be used only for short periods when used systemically, because long-term use above the so-called Cushing’s threshold (>7.5 mg/d) significantly increases the risk of massive and sometimes dangerous side effects. Short-term high-dose or local applications usually have no or much less pronounced side effects. Typical side effects of prednisolone Side … Side Effects of Prednisolone

Cabazitaxel

Products Cabazitaxel is released as a concentrate for the preparation of an infusion solution. It has been approved in many countries since 2011 (Jevtana). Structure and properties Cabazitaxel (C45H57NO14, Mr = 835.9 g/mol) is a taxane semisynthetically derived from a constituent of yew needles. It is structurally closely related to docetaxel, which is itself a … Cabazitaxel

Hemorrhoids Causes and Treatment

Symptoms Hemorrhoids are dilations of the vascular cushions in the anal canal. Possible symptoms include: Bleeding, blood on the toilet paper Pressure discomfort, pain, burning, itching. Unpleasant feeling Inflammation, swelling, skin inflammation. Discharge of mucus, oozing Prolapse, protrusion outside the anus (prolapse). Hemorrhoids can be classified according to various criteria. Common is the classification according … Hemorrhoids Causes and Treatment