Products Calcitriol is commercially available in the form of capsules (e.g., Rocaltrol) and as an ointment for psoriasis (Silkis). The active ingredient has been approved in many countries since 1978. The oral solution has been off the market since 2012. The active ingredient content could not be ensured until the end of the shelf life. … Calcitriol Effects and Side Effects
Products Nefazodone was commercially available in tablet form in many countries beginning in 1997 (Nefadar, 100 mg, Bristol Myers Squibb). It was withdrawn from the market again in 2003 because of potential health risks. Structure and properties Nefazodone (C25H32ClN5O2, Mr = 470.0 g/mol) is present in drugs as nefazodone hydrochloride, a white crystalline powder that … Nefazodon
Treating diseases with the help of medicinal plants is one of the oldest achievements of mankind. One can even say that phytotherapy was the most important medical doctrine of all until the end of the 19th century. In the 16th century, Paracelsus had begun to systematically summarize the medicinal herbs native to our country and … Phytopharmaceuticals: Healing with Plants
Products Daclatasvir was approved in the EU in 2014 and in many countries in 2015 in film-coated tablet form (Daklinza, Bristol-Myers Squibb). Structure and properties Daclatasvir (C40H50N8O6, Mr = 738.9 g/mol) is present in the drug product as daclatasvir dihydrochloride. Effects Daclatasvir (ATC J05AX14) has antiviral properties. The effects are due to binding to the … Daclatasvir
In commercial kitchens, mayonnaise is often produced in-house. What ingredients may a mayonnaise legally contain? What is the most effective way to store mayonnaise and how long may it be offered to diners after production? Mayonnaises, remoulades or dressings are emulsified sauces. Like various condiments or barbecue sauces, these are categorized as delicatessen sauces. Emulsified … Mayonnaises, Remoulades and Dressings
Products D-mannose is available as a medical device in many countries and is commercially available as powder and in tablet form from various suppliers. Structure and properties The α-D-mannose (C6H12O6, Mr = 180.2 g/mol) is a naturally occurring simple sugar (a monosaccharide), which belongs to the aldohexoses and carbohydrates. It exists as a white powder … D-Mannose
Products Pitolisant (formerly tiprolisant) is commercially available in the form of film-coated tablets (Wakix). It was approved in the EU in 2016, in many countries in 2018, and in the United States in 2019. Structure and properties Pitolisant (C17H26ClNO, Mr = 295.8 g/mol) is a piperidine derivative and an ether. Effects Pitolisant (ATC N07XX11) is … Pitolisant
Products Pimavanserin was approved in the United States in 2016 in tablet form (Nuplazid). It has not yet been registered in many countries. Structure and properties Pimavanserin (C25H34FN3O2, Mr = 427.6 g/mol) is present in the drug as pimavanserine tartrate, which is highly soluble in water. It is a urea, fluorobenzyl, and piperidine derivative. Effects … Pimavanserin
Products Sertraline is commercially available as film-coated tablets and as an oral concentrate (Zoloft, generic). It was first released in the United States in 1991 and became a blockbuster. It was approved in many countries in 1993. Structure and properties Sertraline (C17H17Cl2N, Mr = 306.2 g/mol) is present in drugs as sertraline hydrochloride, a white … Sertraline
Products Pyridoxine has been approved in many countries as a monopreparation in tablet form since the 1950s for pregnancy nausea (Benadon, vitamin B6 Streuli). In combination with the antihistamine and antiemetic meclozine, it is registered for nausea and vomiting of any origin and motion sickness (Itinerol B6). It is also combined with doxylamine. Structure and … Pyridoxine against Nausea
Products Fosfomycin is commercially available in many countries as granules (Monuril, generics) and has been approved since 1988. Structure and properties Fosfomycin is a derivative of phosphonic acid, an epoxide, and is present in the granules as a trometamol salt. Fosfomycin trometamol (C7H18NO7P, Mr = 259.2 g/mol) is a white, hygroscopic powder that is very … Fosfomycin
Products Pralatrexate is commercially available as an infusion solution (Folotyn). It has been approved in many countries since 2013. Structure and properties Pralatrexate (C23H23N7O5, Mr = 477.5 g/mol) is a folic acid analog and exists as a racemate. It is a white to yellow substance that is soluble in water. Effects Pralatrexate (ATC L01BA05) has … Pralatrexate
