P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein
Brugada syndrome is a congenital, autosomal-dominant inherited cardiomyopathy. The condition is one of the ion channel diseases and results from a mutation. Treatment includes implantation of an automatic defibrillator. What is Brugada syndrome? The heart pumps blood to the individual tissues of the body. The blood supply corresponds to an oxygen, nutrient and messenger supply … Brugada Syndrome: Causes, Symptoms & Treatment
Cobicistat is a medical agent that is used worldwide to treat HIV infection. It is administered exclusively in a so-called HIV combination therapy, i.e. Cobicistat is only used together with other HIV drugs. This enables a holistic fight against the virus, since cobicistat itself has no independent effectiveness against HI viruses. What is cobicistat? Cobicistat … Cobicistat: Effects, Uses & Risks
Congenital myasthenic syndrome is genetic and belongs to the group of myasthenic syndromes. It is characterized by a disturbance in signal transmission between nerve and muscle cells. The symptoms of this group of disorders vary greatly in severity. In some patients, the particular phenotype of limb-girdle myasthenia is observed. What is congenital myasthenic syndrome? Congenital … Congenital Myasthenic Syndrome: Causes, Symptoms & Treatment
