Causes There are three main factors that cause thromboses in the leg, which are summarized under the name Virchow Trias. These include changes in the inner walls of blood vessels, changes in blood flow and disturbances in the composition of the blood. Vascular walls change in connection with injuries, when scars are formed and through … Causes | Thrombosis in the leg
The Pill The most risky of all contraceptive pills is the combined preparation of estrogen and progestin, because it contains the substance drospirenone. Studies have shown that it carries the greatest risk of thrombosis. It is statistically interesting that only 3-6 out of 10,000 women are affected. Smoking increases the risk of thrombosis, as do … The Pill | Thrombosis in the leg
Therapy Thromboses in the leg indicate that blood clots no longer dissolve properly. Therapeutically, therefore, substances are generally used to reactivate this mechanism. Heparin is the agent of choice here, it prevents the formation of further thromboses. To dissolve the thrombosis in the leg, a recanalization can also be performed. In this procedure, the vein … Therapy | Thrombosis in the leg
Consequences of a thrombosis in the leg By far the most feared consequence of a thrombosis in the leg is pulmonary embolism. It occurs when the thrombus loses its adhesion to the vessel wall and is transported with the bloodstream into the lung, where it closes an artery. This occurs when the leg is moved, … Consequences of a thrombosis in the leg | Thrombosis in the leg
Duration of incapacity to work Whether a thrombosis results in partial or complete incapacity to work depends on the type of work and the severity of the illness. In principle, the doctor treating the patient should always make a recommendation.Shortly after a fibrinolysis (thrombus dissolution) or surgery, the patient is ill. People who perform work … Duration of incapacity to work | Thrombosis in the leg
Pregnancy Pregnancy and puerperium are factors that greatly increase the risk of developing thrombosis in the leg. In fact, thrombotic diseases are the most common cause of death during pregnancy and shortly after birth. This results from the hormonal changes in the body during pregnancy. Pregnancy hormones, such as progesterone, dilate the veins so that … Pregnancy | Thrombosis in the leg
What is a tyrosine kinase? Tyrosine kinase is a specific group of enzymes that are functionally assigned to protein kinases in a biochemical sense. Protein kinases reversibly (possibility of back-reaction) transfer phosphate groups to the OH group (hydroxy group) of the amino acid tyrosine. The phosphate group is transferred to the hydroxy group of the … The tyrosine kinase
What is the tyrosine kinase receptor? The tyrosine kinase receptor represents a membrane-bound receptor, i.e. a receptor anchored in the cell membrane. Structurally, it is a receptor with a transmembrane complex. This means that the receptor passes through the entire cell membrane and also has an extra- and intracellular side. On the extracellular side, the … What is the tyrosine kinase receptor? | The tyrosine kinase
For which indications are they used? Tyrosine kinase inhibitors are used for various malignant diseases. Imatinib is used in particular in chronic myeloid leukemia. Further applications are non-small cell lung cancer (NSCLC), breast cancer and colon cancer. Due to the highly selective attack mechanism of tyrosine kinase inhibitors, they are generally better tolerated than conventional … For which indications are they used? | The tyrosine kinase
Medical: Hypoglycemia Epidemiology In diabetics, hypoglycemia occurs about once or twice a week. Responsible for the regulation of the blood sugar level are on the one hand the sugar intake with food (exogenous supply), on the other hand different hormones like insulin and glucagon as well as the sugar consumption of the body by its … Hypoglycemia
Prognosis Slight hypoglycaemia in itself does not pose a great danger. However, there is a risk that the body gets used to low blood sugar levels and the perception of hypoglycaemia no longer functions. On the other hand, if recurrent severe hypoglycaemia is not treated, it can cause damage to the brain (for example, dementia). … Prognosis | Hypoglycemia
What is labor pains? The pain during labor is also called labor pains. Pain during labor feels different depending on the intensity and frequency, as well as the type of contractions. Contractions occur not only immediately before and during birth, but already from the 20th week of pregnancy. These pregnancy contractions usually have only a … Pain in labour
