Sertraline: Effects, uses, side effects

How sertraline works The active ingredient sertraline belongs to the group of “selective serotonin reuptake inhibitors” (SSRIs): it inhibits the reuptake of serotonin into its storage cells. This increases the amount of free and thus active serotonin, which has a mood-lifting, activating and anxiety-relieving effect. According to current knowledge, this balance of neurotransmitters is often … Sertraline: Effects, uses, side effects

Slimming Products

Effects Antiadiposita differ in their effects. They inhibit appetite or increase satiety, reduce the absorption of food components in the intestine or promote their utilization, increase energy metabolism and degrading metabolic processes. The ideal slimming agent would enable rapid, high and stable weight loss and at the same time be very well tolerated and applicable … Slimming Products

Dasotralin

Products Sunovion’s dasotraline is in the regulatory phase and is therefore not yet available. Structure and properties Dasotralin (C16H15Cl2N, Mr = 292.2 g/mol) is a diastereomer of the desmethyl metabolite of sertraline (Zoloft, generics). Effects Dasotraline selectively inhibits the reuptake of the neurotransmitters dopamine and norepinephrine into presynaptic neurons in the central nervous system. The … Dasotralin

Interactions with Grapefruit Juice

Background That grapefruit juice can cause drug-drug interactions was discovered by chance in a clinical trial in 1989 and confirmed in an experiment by the same research group in 1991 (Bailey et al, 1989, 1991). This showed that simultaneous ingestion of grapefruit juice with the calcium channel blocker felodipine significantly increases the bioavailability of felodipine. … Interactions with Grapefruit Juice

Sertraline: Effects, Uses & Risks

The drug sertraline belongs to the selective serotonin reuptake inhibitors (SSRIs). These are used primarily for the treatment of depression. What is sertraline? The drug sertraline belongs to the selective serotonin reuptake inhibitors (SSRIs). These are used primarily for the treatment of depression. The antidepressant sertraline, like the antidepressants citalopram and fluoxetine, belongs to the … Sertraline: Effects, Uses & Risks

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment

Sertraline

Products Sertraline is commercially available as film-coated tablets and as an oral concentrate (Zoloft, generic). It was first released in the United States in 1991 and became a blockbuster. It was approved in many countries in 1993. Structure and properties Sertraline (C17H17Cl2N, Mr = 306.2 g/mol) is present in drugs as sertraline hydrochloride, a white … Sertraline

Zoloft

ExplanationDefinition Zoloft® is an antidepressant that belongs to the group of selective serotonin reuptake inhibitors (SSRIs). It is characterized in particular by the fact that it does not attenuate (sedate) and is also used for a variety of disorders. Trade names Gladem®Zoloft®Sertralin-ratiopharm®. Chemical name (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-terahydro-N-methyl-1-naphtylamine Active ingredient Sertraline Depression OCD Panic Attack Posttraumatic Stress Disorder … Zoloft