Introduction – What is a chromosomal aberration? A chromosomal aberration describes a deviation from the normal human chromosome configuration. A normal human chromosome set has 23 chromosome pairs of the same kind, which contain the entire genetic material. A chromosomal aberration can be both a numerical and a structural deviation of the chromosome set. Chromosomal … Chromosomal aberration – What is meant by this?
Causes of chromosomal aberration There are different causes for the numerical and structural chromosomal aberrations. The numerical chromosomal aberration has a different number of chromosomes, but the chromosomes themselves look normal. In aneuploidy, single chromosomes are duplicated or missing, as in trisomy 21, for example, the most common cause is non-disjunction of chromosomes during meiosis. … Causes of chromosomal aberration | Chromosomal aberration – What is meant by this?
CLINICAL: Which diseases are caused by chromosomal aberration? Chromosomal aberrations are responsible for a large number of spontaneous abortions before birth and for many diseases. Of all of these, five diseases in particular are widespread. The best known of these is trisomy 21, better known as Down’s syndrome. These children are conspicuous for their short … CLINICAL: Which diseases are caused by chromosomal aberration? | Chromosomal aberration – What is meant by this?
