Products Cabazitaxel is released as a concentrate for the preparation of an infusion solution. It has been approved in many countries since 2011 (Jevtana). Structure and properties Cabazitaxel (C45H57NO14, Mr = 835.9 g/mol) is a taxane semisynthetically derived from a constituent of yew needles. It is structurally closely related to docetaxel, which is itself a … Cabazitaxel
Products Trastuzumab emtansine is commercially available as a sterile powder for the preparation of an infusion solution concentrate (Kadcyla). It has been approved in many countries since 2013. Structure and properties Trastuzumab emtansine is an antibody-drug conjugate that targets HER2. It consists of the anti-HER2 antibody trastuzumab (Herceptin), which is also linked via a linker … Trastuzumab Emtansine
Products Docetaxel is commercially available as an infusion preparation (Taxotere, generics). It was approved in many countries in 1996 as a second taxane after paclitaxel (Taxol). Structure and properties Docetaxel (C43H53NO14, Mr = 807.9 g/mol) is present in the drug as docetaxel trihydrate, a white powder that is practically insoluble in water. The lipophilic drug … Docetaxel
