Thomapyrin® is a combination preparation consisting of the active ingredients paracetamol, acetylsalicylic acid (ASS) and caffeine. It is marketed by Boehringer Ingelheim Pharma GmbH & Co. KG (Vienna, Austria). It is one of the most widely used over-the-counter pain-relieving drugs in Germany. Thomapyrin® is mostly used to relieve mild to moderate pain. Composition Thomapyrin® is … Thomapyrin®
Application and dosage Thomapyrin® can be taken by adults and adolescents from 12 years of age for the treatment of mild acute pain to moderately severe pain, e.g. headache and toothache, fever (for pain and fever treatment). Thomapyrin® should not be taken for more than 3-4 days, unless otherwise directed by the treating physician. Up … Application and dosage | Thomapyrin®
Interactions The simultaneous use of various anticoagulants such as ASS 100, clopidogrel, ticagrelor, Xarelto, heparin or Marcumar® increases the risk of bleeding. Problems in the gastrointestinal tract (e.g. ulcers) occur more frequently if other non-steroidal anti-inflammatory drugs/antirheumatic drugs (NSAIDs) or cortisone preparations (corticosteroids) are taken in parallel or alcohol is consumed. The effect of diuretics … Interactions | Thomapyrin®
Pregnancy and lactation Thomapyrin® should not be taken during the first 6 months of pregnancy. The inhibition of cyclooxygenase by ASA and the resulting lack of prostaglandins can lead to errors in the development of the child. If it is necessary to take Thomapyrin®, the lowest possible doses should be used. Thomapyrin® must never be … Pregnancy and lactation | Thomapyrin®
Contraindications Who should not take paracetamol: Patients with an allergy to the active ingredient paracetamol or other drug components. Patients with severe impairment of liver function Patients with severe impairment of kidney function Patients in pregnancy and breastfeeding ((See also: Paracetamol in the breastfeeding period) Intake possible, but always as short as possible and only … Contraindications | Paracetamol
Introduction Paracetamol is a widely used painkiller (analgesic) from the group of cyclooxygenase inhibitors (non-opioid analgesics) and is used for mild to moderate pain of various causes. It is also used as a fever-reducing drug (antipyretic). Various dosage forms such as: are commercially available. The most common dosage form is 500 mg tablets. Tablets Capsules … Paracetamol
Dosage form TabletsFilm coated tablets Capsules Juice SuppositorySuppositories Syrup Effect By inhibiting the production of prostaglandin in the body’s cells, paracetamol has a fever-reducing and pain-relieving effect. Prostaglandins are so-called pain mediators that regulate functions such as pain, inflammation and fever. Prostaglandins also influence blood clotting. However, the influence of paracetamol on blood clotting is … Dosage form | Paracetamol
Side effects Paracetamol is a well tolerated drug. There are no frequent side effects when used properly. Rare to very rare side effects are Disturbance of blood formation Allergic reactions Stomach pain/nausea Increase in liver enzymes Cramping of the airwaysDistress The active ingredient is completely metabolized in the liver after about 2 hours. If the … Side effects | Paracetamol
Paracetamol in the nursing period Many authors consider the intake of paracetamol during the lactation period to be harmless. According to them there would be experiences for 40 years, which let Paracetamol be the means of the 1st choice in the lactation period. Other authors see it differently. They assume connections between ADHS and the … Paracetamol in the nursing period | Paracetamol
Paracetamol vs. Ibuprofen – what is the difference? Paracetamol and ibuprofen both belong to the so-called non-opioid analgesics. This means that they are both painkillers that do not belong to the group of opiates. They both intervene in the so-called prostaglandin synthesis. Paracetamol belongs to the group of analgesics that are non-opioid. Ibubrofen is a … Paracetamol vs. Ibuprofen – what is the difference? | Paracetamol
Introduction Paracetamol is a painkiller from the group of non-opioid analgesics. It has analgesic and antipyretic effects. The name of the active ingredient is derived from the chemical name of the substance, i.e. from paraacetylaminophenol. Paracetamol belongs to the group of the most important analgesics, as it is normally very well tolerated. In Germany, paracetamol … The Paracetamol suppository
Effective period The duration of action of the paracetamol suppositories depends on the dose of the suppository. On average the suppositories work for 6 to 8 hours, slightly longer in infants and slightly shorter in adults. Therefore, babies younger than three months and weighing three to four kilograms can take two suppositories a day with … Effective period | The Paracetamol suppository