Symptoms The leading symptoms of bacterial vaginosis include: Thin, homogeneous vaginal discharge with a grayish-white color. Unpleasant odor of fish due to the release of volatile amines. It is not accompanied by vaginal inflammation and immune response – therefore it is called vaginosis and not vaginitis. The disease is often asymptomatic. A burning sensation, itching … Bacterial Vaginosis: Symptoms, Causes, Treatment
Indications Infections with protozoa Agents 1. agents for amebiasis, trichomoniasis, and giardiasis: nitroimidazoles: Metronidazole (Flagyl, generic). Tinidazole (Fasigyn, off label). Ornidazole (Tiberal) Other: Atovaquone (Wellvone) Other, not commercially available in this indication: Clioquinol Chlorquinaldol Emetine 2. antimalarials: See under antimalarials 3. agents against leishmaniasis and trypanosomiasis: Pentamidine isethionate (pentacarinate). Eflornithine (Vaniqa, not commercially available for … Antiprotozoal Agent
Products Tinidazole (Fasigyn, 500 mg) is no longer available as a finished drug in many countries. It had been approved since 1973. Drugs containing the active ingredient can be imported from abroad or prepared in a pharmacy as an extemporaneous preparation. A substitute is metronidazole (Flagyl, generic). Structure and properties Tinidazole (C8H13N3O4S, Mr = 247.3 … Tinidazole
Symptoms In women, trichomoniasis manifests as inflammation of the vaginal mucosa with redness, swelling, and a frothy, thin, yellowish-green, foul-smelling discharge. The urethra and cervix may also be infected. The type of discharge varies. In addition, there may be itching, small skin bleeding, and pain during sexual intercourse and urination. In men, the disease is … Trichomoniasis
Effect Nitroimidazoles are antibacterial (bactericidal) and antiparasitic. They are reduced under anaerobic conditions to cytotoxic metabolites that covalently bind to and damage DNA. The damage may take the form of loss of helical structure, impaired matrix function, or strand breaks, leading to inhibition of DNA synthesis. Indications Spectrum: gram-positive and gram-negative anaerobic bacteria and some … Nitroimidazole
