Nitroimidazoles

Tinidazole

Products Tinidazole (Fasigyn, 500 mg) is no longer available as a finished drug in many countries. It had been approved since 1973. Drugs containing the active ingredient can be imported from abroad or prepared in a pharmacy as an extemporaneous preparation. A substitute is metronidazole (Flagyl, generic). Structure and properties Tinidazole (C8H13N3O4S, Mr = 247.3 … Tinidazole

Secnidazole

Products Secnidazole was approved in the United States in 2017 in granular form (Solosec). The substance is not new; it was developed in the 20th century. Structure and properties Secnidazole (C7H11N3O3, Mr = 185.2 g/mol) is an imidazole derivative (nitroimidazole) nitrated at position 5. It is a prodrug that is activated in bacteria. Effects Secnidazole … Secnidazole