Cycloserine

Products No finished drug products containing cycloserine are commercially available in many countries. Structure and properties Cycloserine (C3H6N2O2, Mr = 102.1 g/mol) is a natural substance formed by and is also produced synthetically. It exists as a white powder that is soluble in water. Effects Cycloserine (ATC J04AB01) has antibacterial properties against . The effects … Cycloserine

Ethambutol

Products Ethambutol is commercially available in the form of film-coated tablets (Myambutol, combination products). It has been approved in many countries since 1967. Structure and properties Ethambutol (C10H24N2O2, Mr = 204.3 g/mol) is present in drugs as ethambutol dihydrochloride, a white, crystalline, hygroscopic powder that is readily soluble in water. Effects Ethambutol (ATC J04AK02) has … Ethambutol

Isoniazid

Products Isoniazid is commercially available in tablet form (eg, Isoniazid Labatec, combination products). Structure and properties Isoniazid (C6H7N3O, Mr = 137.1 g/mol) exists as a white crystalline powder or colorless crystals and is readily soluble in water. It is also known as isonicotinylhydrazine (INH). Effects Isoniazid (ATC J04AC01) has bacteriostatic to bactericidal properties against . … Isoniazid

Antibiotics: Antibacterial Drugs

Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs

Phytomenadione

Products Phytomenadione is commercially available as a solution for injection and a solution for oral use (Konakion MM). It has been approved in many countries since 1987. Structure and properties Phytomenadione (C31H46O2, Mr = 450.7 g/mol) is a mixture of -phytomenadione, -phytomenadione, and -epoxyphytomenadione. It exists as a clear, intense yellow, viscous, oily liquid and … Phytomenadione

Bedaquiline

Products Bedaquiline was approved in the United States in 2012 and in the EU in 2014 in tablet form (Sirturo). Structure and properties Bedaquiline (C32H31BrN2O2, Mr = 555.5 g/mol) is a diarylquinoline. It is present in the drug as bedaquiline fumarate, a white powder that is practically insoluble in water. Effects Bedaquiline (ATC J04AK05) has … Bedaquiline

Rifabutin

Products Rifabutin is commercially available in capsule form (mycobutin). It has been approved in many countries since 1994. Structure and properties Rifabutin (C46H62N4O11, Mr = 847 g/mol ) is a semisynthetic ansamycin antibiotic. It exists as a reddish purple amorphous powder that is sparingly soluble in water. Effects Rifabutin (ATC J04AB04) has antibacterial properties against … Rifabutin

Rifampicin

Products Rifampicin is commercially available as film-coated tablets, coated tablets, capsules, and injectables (Rimactan, generics). In addition to mono, various combination preparations are also available. Rifampicin has been approved in many countries since 1968. This article refers to peroral monotherapy. Structure and properties Rifampicin (C43H58N4O12, Mr = 823 g/mol) exists as a reddish brown to … Rifampicin

Pyrazinamide

Products Pyrazinamide is commercially available in tablet form (Pyrazinamide Labatec, combination products). It was first used in the 1950s for the treatment of tuberculosis. Structure and properties Pyrazinamide (C5H5N3O, Mr = 123.1 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is a 1,4-pyrazine and an amide. Pyrazinamide is an … Pyrazinamide

Tuberculostatics

Effect Antituberculous: bacteriostatic to bactericidal (antimycobacterial). Indications Tuberculosis Active substances Antibiotics: Bedaquiline Cycloserine Delamanid Ethambutol Isoniazid Pyrazinamide Rifampicin Rifabutin Streptomycin Thioacetazone