Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Nasal Polyps

Symptoms Nasal polyps are usually bilateral and localized benign mucosal protrusions of the nasal cavity or sinuses. The leading symptom is nasal constriction leading to a change in voice quality. Other possible symptoms include a watery discharge (rhinorrhea), impaired sense of smell and taste, pain and a feeling of fullness in the head. Nasal polyps … Nasal Polyps

Zafirlukast

Products Zafirlukast was commercially available in the form of film-coated tablets (Accolate, off label). It was approved in many countries in 1998. It was discontinued from distribution in 2019. Montelukast is a suitable substitute. Structure and properties Zafirlukast (C31H33N3O6S, Mr = 575.7 g/mol) exists as a fine, white to pale yellow, amorphous powder that is … Zafirlukast

Urticaria: Causes and Treatment

Symptoms Urticaria is a skin disorder that manifests itself in the following symptoms: Temporary wheals with a diameter of millimeters to centimeters, which recede on their own within minutes to hours. Itching, burning and redness of the skin. Angioedema, which is a swelling of the lower skin or mucosal tissue that may be accompanied by … Urticaria: Causes and Treatment

Leukotriene Antagonists

Products Leukotriene antagonists are commercially available as film-coated tablets, granules, and chewable tablets. Structure and properties The active ingredients do not have a uniform chemical structure. Effects The leukotriene antagonists (ATC R03DC) have antiasthmatic, anti-inflammatory, bronchodilator, and antiallergic properties. They bind to the CysLT1 receptor, thereby inhibiting the effects of the cysteinyl leukotrienes LTC4, LTD4, … Leukotriene Antagonists

Cold Urticaria

Note See also the following page: cholinergic urticaria. Symptoms Localized or generalized depending on exposure. Cold-exposed areas of the body are often affected, such as the face: wheals, redness, itching, burning, angioedema. Systemic accompanying symptoms such as fever, chills, pain, headache; complications such as anaphylaxis, respiratory distress, collapse (see below). Symptoms usually appear shortly after … Cold Urticaria

Montelukast

Products Montelukast is commercially available as film-coated tablets and as granules and chewable tablets for children (Singulair, generic). It has been approved in many countries since 1998. Structure and properties Montelukast (C35H36ClNO3S, Mr = 586.18 g/mol) is a chloroquinoline derivative. It is present in drugs as montelukast sodium, a white crystalline powder that is readily … Montelukast