Toxoplasmosis Diagnostics

1st order laboratory parameters – obligatory laboratory tests.

  • Small blood count
  • Differential blood count
  • CRP (C-reactive protein) – inflammatory parameter.
  • ESR (erythrocyte sedimentation rate) – inflammatory parameter.
  • Direct microscopic detection of the pathogen in the blood.
  • Toxoplasma gondii antibody detection (IgM/IgG detection in immunofluorescence).

Pregnant women should be reassayed serologically 14 days after a positive IgM test.

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Toxoplasma gondii DNA detection.
  • Gamma-GT (gamma-glutamyl transferase), ALT (alanine aminotransferase; GPT), AST (aspartate aminotransferase; GOT), GLDH (glutamate dehydrogenase), alkaline phosphatase, bilirubin – for liver function.
  • Creatinine, urea, uric acid – because of renal function.
  • CSF examination in the case of involvement of the central nervous system.
  • TPHA search test in suspected syphilis (lues).
  • HIV antibody screening test
  • EBV antibody test for suspected Epstein-Barr infection.
  • Rubella antibody test
  • Tuberculin test or test for acid-fast rods in suspected tuberculosis.
  • Blood tests for pathogens such as histoplasmosis, herpes simplex virus or varicella zoster virus.