Zinc Ointment: Effects, Side Effects, Interactions, Uses

Products

Among the best-known zinc ointments in many countries are Oxyplastin, ZinCream and Penaten cream. Other ointments contain zinc oxide (e.g., almond oil ointments) and it is also possible to make them in the pharmacy (e.g., zinc paste PH, zinc oxide ointment PH). Congo ointment is no longer on the market as a finished drug, but it is still produced. Galenically, they are pastes and not ointments.

Structure and properties

Zinc ointments are pastes with a high content of zinc oxide (ZnO, Mr = 81.4 g/mol), a white to slightly yellowish white, amorphous, soft powder that is practically insoluble in water. In addition to zinc oxide, other active ingredients such as plant extracts may be present. The ointment base, such as lanolin or almond oil, is also partly responsible for the effects.

Effects

Zinc ointments have drying (adsorptive), astringent, skin-protecting, wound-healing, and mild antiseptic properties. The effects are due to the release of zinc ions from the ointment.

Indications

Indications for use include:

  • Prevention and treatment of diaper dermatitis resp. a rash in the diaper area.
  • Skin wolf (intertrigo)
  • Soreness
  • Small skin damage, e.g. small skin cracks, abrasions, cuts.
  • Wound edge treatment, to support wound healing.
  • As a skin protection ointment, for example, in a treatment with wart remedies or with a urea ointment.

Dosage

According to the package leaflet. The ointment is applied once to several times a day, depending on the indication.

Contraindications

Zinc ointment is contraindicated in case of hypersensitivity. Full precautions can be found in the drug label.

Interactions

Attenuation of the effects of other topical medications has been described.

Adverse effects

Possible adverse effects include hypersensitivity reactions and local reactions. Zinc ointments may temporarily stain clothing and objects white.