Anorexia Nervosa: Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests.

  • Small blood count [anemia Anemia): 40% of cases, usually iron deficiency anemia; leukocytopenia (decreased number of leukocytes (white blood cells) in the blood): 30% of cases, mostly granulopenia (decreased number of granulocytes, belong to the leukocyte group, in the blood); thrombocytopenia (decreased number of platelets (blood cells) in the blood): 10% of cases]
  • Electrolytessodium, potassium, calcium [hypokalemia (potassium deficiency), esp. in purging behavior, i.e., vomiting or laxative abuse/abuse]
  • Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, ketone, urobilinogen, bilirubin, blood), sediment, if necessary urine culture (pathogen detection and resistogram, that is, testing of suitable antibiotics for sensitivity / resistance).
  • Fasting glucose (fasting blood glucose), if necessary oral glucose tolerance test (oGTT).
  • Pancreatic parameters – amylase, elastase (in serum and stool), lipase.
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin [transaminase elevation: liver values often increased 2 to 4 times, rarely also > 1,000 U/l].
  • LDH (lactate dehydrogenase) – enzyme, which can be increased in many different diseases such as anemia (anemia) or cancer.
  • Renal parameters – urea, creatinine, possibly cystatin C or creatinine clearance.
  • Total protein
  • Albumin (prealbumin)
  • Total cholesterol, LDL cholesterol, HDL cholesterol
  • Zinc

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • LH (luteinizing hormone).
  • FSH (follicle stimulating hormone)
  • 17-beta estradiol
  • Thyroid parameters – TSH, fT3, fT4 [lowering of fT3 with normal fT4 and TSH as a physiological phenomenon of underweight].
  • Cortisol
  • PRL (prolactin)
  • STH (hGH)
  • Creatine kinase [increase during excessive exercise].
  • SS-crosslaps – due tobone metabolism, osteoporosis diagnosis and screening.
  • Leptin – peptide hormone involved in the control of hunger and satiety [leptin ↓; as serum leptin levels fall, physical activity increases at the same time].