At what pH value does Trypsin work best? | Trypsin

At what pH value does Trypsin work best?

Trypsin, like most other digestive enzymes, can only work properly at a certain pH. The optimal pH range for trypsin is between 7 and 8, which corresponds to the pH range in the small intestine of a healthy person. If this range changes, trypsin can no longer work sufficiently and this can lead to a disturbance in the absorption of proteins from food.

Production of Trypsin

Trypsin, like many other digestive enzymes, is produced in the pancreas, more precisely in the exocrine part of the pancreas. There it is first released as proenzyme trypsinogen and then converted into an active form in the small intestine by the enzyme entereopeptidase, which in turn can activate other digestive enzymes.