Products
Certoparin was commercially available as a solution for injection (Sandoparin, off label). It was approved in many countries from 1989 to 2018.
Structure and properties
Certoparin is present in drugs as certoparin sodium.
Effects
Certoparin (ATC B01AB01) has antithrombotic properties. The effects are primarily due to inhibition of coagulation factor Xa by complexation with antithrombin III. Protamine may be used as an antidote in cases of severe overdose.
Indications
For prevention of postoperative venous thrombosis and pulmonary embolism.
Dosage
According to the SmPC. The solution for injection is administered subcutaneously.
Contraindications
For complete precautions, see the drug label.
Interactions
Drug-drug interactions are possible with drugs that affect blood clotting.
Adverse effects
The most common possible adverse effects include local reactions at the injection site, redness, bleeding, and an increase in transaminases.
