Devil’s Claw: Effect and Side Effects

The iridoids contained in the roots are bitter substances that excite bitter receptors on the taste buds of the base of the tongue. This results in an increase in salivary and gastric secretion, thus stimulating appetite and promoting digestion.

How devil’s claw promotes digestion

Other mechanisms that promote digestion include:

  • The lowering of the pH in the stomach
  • The stimulation of bile secretion (choleretic effect).
  • The increase in intestinal movements and the improvement of the activity of various digestive enzymes.

Action against inflammation

Furthermore, the devil’s claw root is also said to have an anti-inflammatory (antiphlogistic) and weak analgesic (analgesic) effect, which is probably also due to the iridoids and phenylethanol derivatives.

Devil’s claw: side effects

Very rarely, hypersensitivity reactions such as hives, rash, and even shock may occur when taking devil’s claw preparations. Rarely, nausea, vomiting, diarrhea, headache and dizziness are also observed.

Interactions with other agents are not currently known.